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Dr. 이정은
Dr. Lee Jung Eun
소속병원
삼성서울병원
진료과목
신장내과
예약전화
02-3410-3000
전문분야
사구체신질환
당뇨성신질환
만성신부전
혈액투석
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422
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[ 당뇨 신질환의 임상 역학 연구 및 새로운 예후 인자 발굴 ]
당뇨 신질환은 당뇨병의 가장 심각한 합병증으로 당뇨 환자의 예후를 결정하는 가장 중요한 인자인데, 당뇨병의 증가와 당뇨 환자의 생존률 향상에 따라 그 유병률은 점점 증가하고 있다. 또한 의학의 발전에도 불구하고 당뇨 신질환에서 말기 신부전으로 진행하는 위험도는 크게 호전되지 못하였음이 여러 역학 연구에서 확인되었다. 따라서, 당뇨 신질환에 대한 새로운 치료의 개발은 현대 의학의 시급한 과제이다. 새로운 치료법 개발의 어려움 중 하나는 당뇨 신질환의 자연 경과가 다양하기 때문이며, 따라서 질병의 자연 경과를 보다 더 잘 이해하고 고위험군을 분류해 내는 것이 필수적이다. 본인은 하버드 의과대학 부속 조슬린 당뇨 센터에서 2년간 연수하면서 당뇨 신질환의 역학 연구와 여러 가지 다양한 바이오마커들의 예후인자로서의 가능성을 평가하였다. 현재는 한국인에서의 당뇨 신질환의 역학 연구 진행을 위해 계획 수립 중이며, 당뇨 신질환의 신생검 조직에서 바이오마커들의 표현 정도를 분석하여 질병의 발생 기전에 대한 연구를 함께 진행하고 있다.
학력
2005.08 서울대학교 대학원 의학박사
2003.08 서울대학교 대학원 의학석사
1998.02 서울대학교 의과대학 의학과
경력
2019.04 ~현재 성균관의대 내과학 교수
2013.09 ~현재 삼성서울병원 신장내과 의국장
2005.03 ~현재 삼성서울병원 신장내과 전문의
2013.04 ~ 2019.03 성균관의대 내과학 부교수
2009.03 ~ 2013.03 성균관의대 내과학 조교수
2011.03 ~ 2013.02 미국 보스톤 Joslin Diabetes Center, Harvard Medical School 연수
2007.03 ~ 2009.02 성균관의대 내과학 임상조교수
2005.03 ~ 2007.02 성균관의대 내과학 임상전임강사
2003.03 ~ 2005.02 서울대학교 병원 내과 전임의
1999.03 ~ 2003.02 서울대학교 병원 레지던트
1998.03 ~ 1999.02 서울대학교 병원 인턴
논문
AM J TRANSPLANT 2019 10.1111/ajt.15711
The combination of area under the curve and percentage change in estimated glomerular filtration rate predicts long-term outcome of kidney transplants
Lee1, EJ; Jeon, J; Lee, KW; Yoo, H; Jang, HR; Park, JB; Lee, JE; Kim, K; Huh, W

Ann Intensive Care 2019 10.1186/s13613-019-0534-7
Changes in acute kidney injury epidemiology in critically ill patients: a population-based cohort study in Korea
Hwang1, S; Park, H; Kim, Y; Kang, D; Ku, HS; Cho, J; Lee, JE; Huh, W; Guallar, E; Suh, GY; Jang, HR

BMC NEPHROLOGY 2019 10.1186/s12882-019-1403-1
Creatinine- and cystatin C-based estimated glomerular filtration rate slopes for the prediction of kidney outcome: a comparative retrospective study
Kim1, S; Hwang, S; Jang, HR; Sohn, I; Ahn, HS; Park, HD; Huh, W; Jin, DC; Kim, YG; Kim, DJ; Oh, HY; Lee, JE

TRANSPL P 2019 10.1016/j.transproceed.2018.10.026
Clinical Impact of a Protocolized Kidney Donor Follow-up System
Kwon1, HJ; Jeon, J; Kim, DH; Jang, HR; Sung, HH; Han, DH; Park, JB; Lee, JE; Huh, W; Kim, SJ; Kim, YG; Kim, DJ; Oh, HY

J ONCOL 2019 10.1155/2019/8736163
Risk Prediction for Contrast-Induced Nephropathy in Cancer Patients Undergoing Computed Tomography under Preventive Measures
Jeon1, J; Kim, S; Yoo, H; Kim, K; Kim, Y; Park, S; Jang, HR; Kim, DK; Huh, W; Kim, YG; Kim, DJ; Oh, HY; Lee, JE

CRIT CARE 2018 10.1186/s13054-018-2192-9
Association between diuretics and successful discontinuation of continuous renal replacement therapy in critically ill patients with acute kidney injury
Jeon1, J; Kim, DH; Baeg, SI; Lee, EJ; Chung, CR; Jeon, K; Lee, JE; Huh, W; Suh, GY; Kim, YG; Kim, DJ; Oh, HY; Jang, HR

CLIN TRANSPLANT 2018 10.1111/ctr.13372
Ten-year observational follow-up of a randomized trial comparing cyclosporine and tacrolimus therapy combined with steroid withdrawal in living-donor renal transplantation
Kim1, J; Park, J; Hwang, S; Yoo, H; Kim, K; Park, JB; Jang, HR; Lee, JE; Kim, SJ; Kim, YG; Kim, DJ; Oh, HY; Huh, W

EUR J CLIN INVEST 2018 10.1111/eci.12936
First-year GFR slope and long-term renal outcome in IgA nephropathy
Lee1, K; Shin, J; Park, J; Hwang, S; Jang, HR; Huh, W; Kwon, GY; Kim, YG; Oh, HY; Lee, JE; Kim, DJ

SCI REP-UK 2018 10.1038/s41598-018-23014-0
Nonalcoholic fatty liver disease accelerates kidney function decline in patients with chronic kidney disease: a cohort study
Jang1, HR; Kang, D; Sinn, DH; Gu, S; Cho, SJ; Lee, JE; Huh, W; Paik, SW; Ryu, S; Chang, Y; Shafi, T; Lazo, M; Guallar, E; Cho, J; Gwak, GY

J DIABETES COMPLICAT 2017 10.1016/j.jdiacomp.2017.08.009
Tissue expression of tubular injury markers is associated with renal function decline in diabetic nephropathy
Hwang1, S; Park, J; Kim, J; Jang, HR; Kwon, GY; Huh, W; Kim, YG; Kim, DJ; Oh, HY; Lee, JE

TRANSPL P 2017 10.1016/j.transproceed.2017.09.024
Predictive Factors of Renal Adaptation After Nephrectomy in Kidney Donors
Kwon1, HJ; Kim, DH; Jang, HR; Jung, SH; Han, DH; Sung, HH; Park, JB; Lee, JE; Huh, W; Kim, SJ; Kim, YG; Kim, DJ; Oh, HY

J CLIN SLEEP MED 2017 10.5664/jcsm.6758
Independent Contributions of Obstructive Sleep Apnea and the Metabolic Syndrome to the Risk of Chronic Kidney Disease
Lee1, YJ; Jang, HR; Huh, W; Kim, YG; Kim, DJ; Oh, HY; Joo, EY; Lee, JE

AM J PHYSIOL RENAL RHYSIOL 2017 10.1152/ajprenal.00097.2016
Early, but not late, treatment with human umbilical cord blood-derived mesenchymal stem cells attenuates cisplatin nephrotoxicity through immunomodulation
Park1, JH; Jang, HR; Kim, DH; Kwon, GY; Lee, JE; Huh, W; Choi, SJ; Oh, W; Oh, HY; Kim, YG

Drug Des Devel Ther. 2017 Jan 12;11:203-210. doi: 10.2147/DDDT.S118154. eCollection 2017.
Comparison of the long-term efficacy and safety of generic Tacrobell with original tacrolimus (Prograf) in kidney transplant recipients
Son SY11, Jang HR1, Lee JE1, Yoo H2, Kim K3, Park JB4, Kim SJ4, Oh HY1, Huh W1.

Eur J Intern Med. 2016 Sep;33:88-92. doi: 10.1016/j.ejim.2016.06.028. Epub 2016 Jul 12.
Diagnostic performances of M-protein tests according to the clinical presentations of kidney disease
Koo EH11, Shin JH1, Jang HR1, Park HD2, Kwon GY3, Huh W1, Kim DJ1, Kim YG1, Oh HY1, Lee JE4.

Medicine (Baltimore). 2016 Jul;95(27):e3930.
Risk factors for renal impairment revealed after unilateral adrenalectomy in patients with primary aldosteronism
Kim DH11, Kwon HJ, Ji SA, Jang HR, Jung SH, Kim JH, Kim JH, Lee JE, Huh W, Kim YG, Kim DJ, Oh HY.

Ann Med. 2016;48(3):171-81. doi: 10.3109/07853890.2016.1153805. Epub 2016 Mar 26.
The effects of cytotoxic therapy in progressive IgA nephropathy
Shin JH11, Lee JE1, Park JH1, Lim S2, Jang HR1, Kwon GY2, Huh W1, Jung SH3, Kim YG1, Oh HY1, Kim DJ1.

Int Urol Nephrol. 2016 Mar;48(3):431-9. doi: 10.1007/s11255-015-1163-1. Epub 2015 Nov 18.
The impact of slow graft function on graft outcome is comparable to delayed graft function in deceased donor kidney transplantation
Shin JH11, Koo EH2, Ha SH3, Park JH2, Jang HR2, Lee JE2, Park JB4, Kim SJ4, Jung SH5, Kim YG2, Kim DJ2, Oh HY2, Huh W6.

Am J Physiol Renal Physiol. 2016 Feb 15;310(4):F272-83. doi: 10.1152/ajprenal.00217.2015. Epub 2015 Dec 9.
Aging has small effects on initial ischemic acute kidney injury development despite changing intrarenal immunologic micromilieu in mice
Jang HR11, Park JH1, Kwon GY2, Park JB3, Lee JE1, Kim DJ1, Kim YG1, Kim SJ3, Oh HY1, Huh W4.

Medicine (Baltimore). 2016 Jan;95(1):e2400. doi: 10.1097/MD.0000000000002400.
Risk Factors for Renal Functional Decline in Chronic Hepatitis B Patients Receiving Oral Antiviral Agents
Shin JH11, Kwon HJ, Jang HR, Lee JE, Gwak GY, Huh W, Jung SH, Lee JH, Kim YG, Kim DJ, Oh HY.

Korean J Intern Med. 2015 Jul;30(4):496-505. doi: 10.3904/kjim.2015.30.4.496. Epub 2015 Jun 29.
Clinical features and outcomes of systemic amyloidosis with gastrointestinal involvement: a single-center experience
Lim AY11, Lee JH1, Jung KS1, Gwag HB1, Kim do H1, Kim SJ1, Lee GY1, Kim JS2, Kim HJ3, Lee SY3, Lee JE1, Jeon ES1, Kim K1.

Nephrology (Carlton). 2015 Apr;20(4):279-85. doi: 10.1111/nep.12383.
Comparison of intrarenal renin-angiotensin system activity in diabetic versus non-diabetic patients with overt proteinuria
Park JH11, Jang HR, Lee JH, Lee JE, Huh W, Lee KB, Kwon YJ, Do JY, Kim HY, Kim YG.

Amyloid. 2014 Dec;21(4):261-6. doi: 10.3109/13506129.2014.960560. Epub 2014 Sep 24.
Bortezomib, melphalan, and prednisolone combination chemotherapy for newly diagnosed light chain (AL) amyloidosis
Lee JY11, Lim SH, Kim SJ, Lee GY, Lee JE, Choi JO, Kim JS, Kim HJ, Lee SY, Min JH, Jeon ES, Kim K.

Intern Med J. 2014 Dec;44(12a):1217-22. doi: 10.1111/imj.12591.
Association between pre-donation serum uric acid concentration and change in renal function after living kidney donation in women
Cho A11, Lee JE, Jang HR, Huh W, Kim DJ, Oh HY, Kim YG.

Transplant Proc. 2014 Dec;46(10):3396-9. doi: 10.1016/j.transproceed.2014.04.015.
Comparison of Cadaveric Kidney Transplantation From In-center and External Center Donors
Cho AJ11, Jang HR2, Lee JE2, Huh WS2, Kim YG2, Oh HY2, Kim DJ3.

BMC Cancer. 2014 Dec 3;14:906. doi: 10.1186/1471-2407-14-906.
Increased risk of everolimus-associated acute kidney injury in cancer patients with impaired kidney function
Ha SH1, Park JH, Jang HR, Huh W, Lim HY, Kim YG, Kim DJ, Oh HY, Lee JE1.

Am J Physiol Renal Physiol. 2014 Nov 15;307(10):F1149-61. doi: 10.1152/ajprenal.00555.2013. Epub 2014 Aug 20.
Effect of preemptive treatment with human umbilical cord blood-derived mesenchymal stem cells on the development of renal ischemia-reperfusion injury in mice
Jang HR11, Park JH1, Kwon GY2, Lee JE1, Huh W1, Jin HJ3, Choi SJ3, Oh W3, Oh HY1, Kim YG4.

Drug Des Devel Ther. 2014 Nov 7;8:2241-9. doi: 10.2147/DDDT.S70595. eCollection 2014.
Early non-steady-state population pharmacokinetics of oral cyclosporine in renal transplant recipients
Baek H11, Han S2, Yim DS2, Kim SJ3, Lee SY4, Jang HR5, Lee JE5, Kim DJ5, Kim YG5, Oh HY5, Huh W5.

Crit Care. 2014 Nov 19;18(6):640. doi: 10.1186/s13054-014-0640-8.
Clinical relevance of procalcitonin and C-reactive protein as infection markers in renal impairment: a cross-sectional study
Park JH11, Kim do H2, Jang HR3, Kim MJ4, Jung SH5, Lee JE6, Huh W7, Kim YG8, Kim DJ9, Oh HY10.

Transl Res. 2014 Nov;164(5):400-10. doi: 10.1016/j.trsl.2014.05.009. Epub 2014 May 23.
Clinical relevance of urinary angiotensinogen and renin as potential biomarkers in patients with overt proteinuria
Jang HR11, Jeon J1, Park JH1, Lee JE1, Huh W1, Oh HY1, Kim YG2.

Clin Transplant. 2014 Sep;28(9):953-60. doi: 10.1111/ctr.12388. Epub 2014 Jul 16.
Impact of donor kidney function and donor age on poor outcome of living-unrelated kidney transplantation (KT) in comparison with living-related KT
Park KS11, Shin JH, Jang HR, Lee JE, Huh WS, Kim YG, Oh HY, Kim DJ.

JOURNAL OF NEUROSURGERY, JUN 2014, 120(6):1340-1348, 10.3171/2013.12.JNS13888
Increased risk of acute kidney injury associated with higher infusion rate of mannitol in patients with intracranial hemorrhage Clinical article
Kim MY1, Park JH, Kang NR, Jang HR, Lee JE, Huh W, Kim YG, Kim DJ, Hong SC, Kim JS

PLoS One. 2013;8(3):e58007. doi: 10.1371/journal.pone.0058007. Epub 2013 Mar 20.
Risk of ESRD and All Cause Mortality in Type 2 Diabetes According to Circulating Levels of FGF-23 and TNFR1
Lee JE11, Gohda T, Walker WH, Skupien J, Smiles AM, Holak RR, Jeong J, McDonnell KP, Krolewski AS, Niewczas MA.

Kidney Int. 2013 Feb;83(2):285-92. doi: 10.1038/ki.2012.389. Epub 2012 Dec 19.
A family-based association study after genome-wide linkage analysis identified two genetic loci for renal function in a Mongolian population
Park H11, Kim HJ, Lee S, Yoo YJ, Ju YS, Lee JE, Cho SI, Sung J, Kim JI, Seo JS.

Am J Kidney Dis. 2012 Jul;60(1):74-81. doi: 10.1053/j.ajkd.2012.02.331. Epub 2012 Apr 11.
Effect of an Electronic Alert on Risk of Contrast-Induced Acute Kidney Injury in Hospitalized Patients Undergoing Computed Tomography
Cho A11, Lee JE, Yoon JY, Jang HR, Huh W, Kim YG, Kim DJ, Oh HY.

Am J Physiol Renal Physiol. 2012 Jul 1;303(1):F157-62. doi: 10.1152/ajprenal.00443.2011. Epub 2012 Apr 18.
Elevated urinary excretion of immunoglobulins in nonproteinuric patients with type 1 diabetes
Gohda T11, Walker WH, Wolkow P, Lee JE, Warram JH, Krolewski AS, Niewczas MA.

Ren Fail. 2012;34(3):279-85. doi: 10.3109/0886022X.2011.647293. Epub 2012 Jan 17.
The Role of Nafamostat Mesylate in Continuous Renal Replacement Therapy among Patients at High Risk of Bleeding
Baek NN11, Jang HR, Huh W, Kim YG, Kim DJ, Oh HY, Lee JE.

Nephrol Dial Transplant. 2011 Dec;26(12):4090-4. doi: 10.1093/ndt/gfr229. Epub 2011 May 13.
Statin therapy is associated with improved survival in incident peritoneal dialysis patients: propensity-matched comparison
Lee JE11, Oh KH, Choi KH, Kim SB, Kim YS, Do JY, Kim YL, Kim DJ.

Nephrol Dial Transplant. 2011 Nov;26(11):3496-501. doi: 10.1093/ndt/gfr094. Epub 2011 Mar 15.
Post-operative acute kidney injury in patients with renal cell carcinoma is a potent risk factor for new-onset chronic kidney disease after radical nephrectomy
Cho A11, Lee JE, Kwon GY, Huh W, Lee HM, Kim YG, Kim DJ, Oh HY, Choi HY.

Ren Fail. 2011;33(3):316-22. doi: 10.3109/0886022X.2011.560406.
Incidence, Risk Factors, and Prediction of Acute Kidney Injury After Off-Pump Coronary Artery Bypass Grafting
Kim MY11, Jang HR, Huh W, Kim YG, Kim DJ, Lee YT, Oh HY, Eun Lee J.

Int J Antimicrob Agents. 2010 May;35(5):473-7. doi: 10.1016/j.ijantimicag.2009.12.002. Epub 2010 Jan 20.
Predictors of acute kidney injury associated with intravenous colistin treatment
Kwon JA11, Lee JE, Huh W, Peck KR, Kim YG, Kim DJ, Oh HY.

Exp Mol Med. 2009 Apr 30;41(4):253-8. doi: 10.3858/emm.2009.41.4.028.
Higher mitochondrial DNA copy number is associated with lower prevalence of microalbuminuria
Lee JE11, Park H, Ju YS, Kwak M, Kim JI, Oh HY, Seo JS.

J Korean Med Sci. 2009 Jan;24 Suppl:S22-9. doi: 10.3346/jkms.2009.24.S1.S22. Epub 2009 Jan 28.
The Mildly Elevated Serum Bilirubin Level is Negatively Associated with the Incidence of End Stage Renal Disease in Patients with IgA Nephropathy
Chin HJ11, Cho HJ, Lee TW, Na KY, Oh KH, Joo KW, Yoon HJ, Kim YS, Ahn C, Han JS, Kim S, Jeon ES, Jin DC, Kim YL, Park SH, Kim CD, Song YR, Kim SG, Kim YG, Lee JE, Oh YK, Lim CS, Lee SK, Chae DW, Cho WY, Kim HK, Jo SK; Progressive REnal disease and Medical Informatics and gEnomics Research (PREMIER) members.

J Korean Med Sci. 2009 Jan;24 Suppl:S63-8. doi: 10.3346/jkms.2009.24.S1.S63. Epub 2009 Jan 28.
N-terminal Pro-Brain Natriuretic Peptide Levels Predict Left Ventricular Systolic Function in Patients with Chronic Kidney Disease
Lee JE11, Choi SY, Huh W, Park SW, Kim DJ, Oh HY, Kim YG.

Am J Hypertens. 2007 Nov;20(11):1189-94.
Metabolic syndrome, C-reactive protein, and chronic kidney disease in nondiabetic, nonhypertensive adults
Lee JE11, Choi SY, Huh W, Kim YG, Kim DJ, Oh HY.

Nephron Clin Pract. 2007;106(3):c98-103. Epub 2007 May 22.
Association of metabolic syndrome with microalbuminuria in non-hypertensive type 2 diabetic patients
Lee JE11, Huh W, Son HJ, Kim YG, Kim DJ, Lee MK, Oh HY.

Nephrol Dial Transplant. 2006 Aug;21(8):2338-9. Epub 2006 Mar 22.
Henoch-Schonlein purpura associated with propylthiouracil overdose
Lee JE1, Jeon CH, Chang DK, Lee MS, Oh HY.

Hypertension. 2006 May;47(5):962-7. Epub 2006 Mar 6.
Serum uric acid is associated with microalbuminuria in prehypertension
Lee JE11, Kim YG, Choi YH, Huh W, Kim DJ, Oh HY.
상세정보 펼쳐보기
동병원
동일과
LIST
만성신부전,사구체신질환,복막투석,신장염
월요일오후
화요일오전
화요일오후
목요일오전
사구체신질환
월요일오전
화요일오전
화요일오후
목요일오후
신장이식,만성신부전,혈액투석,당뇨성신증
월요일오전
수요일오전
수요일오후
목요일오후
금요일오전
사구체신질환,신장이식,당뇨성신질환,급성신부전
월요일오전
화요일오전
화요일오후
수요일오전
토요일오전
타병원
동일과
LIST
가톨릭대학교 의정부성모병원
고혈압,사구체질환,당뇨병성신증,만성신부전증
충남대학교병원
신장 질환,고혈압,신장이식,신장투석
한대석내과
신장투석,만성신장염,고혈압
신촌세브란스병원
당뇨병성신증,만성신부전증,부종,신장염
서울대학교병원
신장이식,만성콩팥병,사구체신염,루프스신염
경북대학교병원
만성콩팥질환,말기신부전,신장이식
서울대학교병원
신장이식,다낭성신장,만성신부전,만성콩팥병
가톨릭대학교 서울성모병원
신장이식,췌장이식
고려대학교 구로병원
신장질환,혈관,투석
이대목동병원
신부전증,신장염,고혈압,부종
전남대학교병원
신장질환
아주대학교병원
만성신부전증,신장이식,투석치료
순천향대학교 부천병원
신이식,사구체신염,당뇨병성신증
순천향대학교 부천병원
투석,영양상태,사구체신염
순천향대학교 부천병원
혈관합병증,복막투석,영양상태
순천향대학교 부천병원
사구체신염,급성신손상
순천향대학교 부천병원
급성신손상,중환자의학
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