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교수찾아삼만리

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Dr. 이상훈
Dr. Lee Sang Hun
소속병원
강동경희대학교병원
진료과목
류마티스내과
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1577-5800
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강직성척추염
류마티스관절염
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561
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학력
1999 경희대학교 의과대학 졸업
경력
2000 - 2004 경희의료원 인턴, 내과 레지던트 수료
2004 - 2005 경희의료원 류마티스내과 전임의
2006 - 현재 강동 경희대 병원 류마티스내과 근무, 현재 정교수
2013 1 - 2014 1 스탠포드 대학교 로빈슨 연구실, 방문교수 강직척추염 자가항체 연구
현재 대한류마티스학회 국제위원회 위원
현재 식약처 한국의약품안전과리원 의약품 부작용 전문위원회 전문가단
현재 의료기관평가인증원 환자안전 전문가 자문위원
현재 강동경희대 병원 류마티스 내과 과장, 경희대 의과대학 류마티스 실습학 책임교수2006 2 : 경희대학교 의과대학 내과, 류마티스학 석,박사
논문
Progressive sacroiliitis due to accessory sacroiliac joint mimicking ankylosing spondylitis: A case report (Medicine. 2019;98(16):e15324-15327)
A systemic lupus erythematosus patient with thunderclap headache: reversible cerebral vasoconstriction syndrome (Lupus. 2019;28(7):898-902)
축형 척추관절염의 새로운 약물 치료 (대한내과학회지. 2018;93(5):424-429)
Factors associated with quality of life and functional disability among rheumatoid arthritis patients treated with disease-modifying anti-rheumatic drugs for at least 6 months (INTERNATIONAL JOURNAL OF RHEUMATIC DISEASES. 2018;21(5):1001-1009)
Henoch-Schonlein Purpura With Muscle Involvement, Presenting as Myositis (JCR-JOURNAL OF CLINICAL RHEUMATOLOGY. 2017;23(1):60-62)
Hypocomplementemic Urticarial Vasculitis Syndrome with Membranous Nephropathy: Case Report (JOURNAL OF KOREAN MEDICAL SCIENCE. 2017;32(12):2064-2068)
Radiographic Evidence of Hip Joint Recovery in Patients with Ankylosing Spondylitis after Treatment with Anti-tumor Necrosis Factor Agents: A Case Series (JOURNAL OF RHEUMATOLOGY. 2017;44(11):1759-1759)
Subcutaneous Sarcoidosis Mimicking Cellulitis (JOURNAL OF RHEUMATOLOGY. 2016;43(3):674-675)
Safety of Resuming Tumor Necrosis Factor Inhibitors in Ankylosing Spondylitis Patients Concomitant with the Treatment of Active Tuberculosis: A Retrospective Nationwide Registry of the Korean Society of Spondyloarthritis Research (PLOS ONE. 2016;11(4):0-0)
Full-blown cardiac manifeationas in ankylosing spondylitis (Echocardiogrphay. 2016;33(11):1785-1787)
Complete Remission of Nephrotic Syndrome Without Resolution of Amyloid Deposit After Anti-Tumor Necrosis Factor alpha Therapy in a Patient With Ankylosing Spondylitis (JCR-JOURNAL OF CLINICAL RHEUMATOLOGY. 2016;22(2):86-88)
SAPHO 증후군 환자의 딸에서 발생한 손발바닥고름물집증 (대한류마티스학회지. 2015;22(2):127-131)
Increased expression of endocan in arthritic synovial tissues: Effects of adiponectin on the expression of endocan in fibroblast-like synoviocytes (MOLECULAR MEDICINE REPORTS. 2015;11(4):2695-2702)
강직성 척추염의 병태 생리 (대한류마티스학회지. 2015;22(2):61-68)
Secondary angle closure glaucoma by lupus choroidopathy as an initial presentation of systemic lupus erythematosus: a case report (BMC OPHTHALMOLOGY. 2015;15(0):148-154)
Taurine Ameliorates Hypercholesterolemia But Not Obesity in Rats Fed a Lard-Based, High-Fat Diet (ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY. 2015;803(0):271-278)
The role of adiponectin in the production of IL-6, IL-8, VEGF and MMPs in human endothelial cells and osteoblasts: implications for arthritic joints (EXPERIMENTAL AND MOLECULAR MEDICINE. 2014;46(0):0-0)
Serum level of osteopontin as an inflammatory marker does not indicate disease activity or responsiveness to therapeutic treatments in patients with rheumatoid arthritis (CLINICAL RHEUMATOLOGY. 2014;33(0):397-402)
Renal involvement in ankylosing spondylitis: prevalence, pathology, response to TNF-a blocker (RHEUMATOLOGY INTERNATIONAL. 2013;33(7):1689-1692)
Effect of taurine chloramine on differentiation of human preadipocytes into adipocytes. (ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY. 2013;775(1):247-257)
A Case of Myotonic Dystrophy with Electrolyte Imbalance (JOURNAL OF KOREAN MEDICAL SCIENCE. 2013;28(7):1111-1113)
Taurine chloramine modulates the expression of adipokines through inhibition of the STAT-3 signaling pathway in differentiated human adipocytes (AMINO ACIDS. 2013;45(6):1415-1422)
Musculoskeletal manifestation in the joints of the diabetic animal model Otsuka Long-Evans Tokushima Fatty rat: A histological study (MOLECULAR MEDICINE REPORTS. 2012;5(3):779-782)
류마티스관절염 환자에서 Imatinib Mesylate의 치료 효과 보고 1예 (대한내과학회지. 2012;83(3):405-410)
골수섬유증과 동반된 베체트병 1예 (대한류마티스학회지. 2012;19(1):55-58)
Synergy between adiponectin and interleukin-1β on the expression of interleukin-6, interleukin-8, and cyclooxygenase-2 in fibroblast-like synoviocytes (EXPERIMENTAL AND MOLECULAR MEDICINE. 2012;44(7):440-447)
Hypoxia differentially affects IL-1 beta-stimulated MMP-1 and MMP-13 expression of fibroblast-like synoviocytes in an HIF-1 alpha-dependent manner (RHEUMATOLOGY. 2012;51(3):443-450)
Early Cardiac Valvular Changes in Ankylosing Spondylitis: A Transesophageal Echocardiography Study (Journal of Cardiovascular Ultrasound. 2012;20(1):30-36)
Contribution of TNF-alpha-308 gene polymorphisms to susceptibility to the development of uveitis in Korean patients with HLA-B27-positive ankylosing spondylitis (SCANDINAVIAN JOURNAL OF RHEUMATOLOGY. 2011;40(4):317-318)
Expression levels and association of gelatinases MMP-2 and MMP-9 and collagenases MMP-1 and MMP-13 with VEGF in synovial fluid of patients with arthritis (RHEUMATOLOGY INTERNATIONAL. 2011;31(4):543-547)
전신 홍반 루푸스 환자에서 발생한 전신 농포성 건선 1예 (전북의대 논문집. 2011;35(1):71-75)
Epidermal growth factor increases prostaglandin E-2 production via ERK1/2 MAPK and NF-kappa B pathway in fibroblast like synoviocytes from patients with rheumatoid arthritis (RHEUMATOLOGY INTERNATIONAL. 2010;30(4):443-449)
chronic necrotizing pulmonary aspergillosis in a patient treated with a tumor necrosis factor-alpha inhibitor (International Journal of Rheumatic disease. 2010;13(0):e16-e19)
Clinical Images: Aggressive gouty arthritis with concurrent involvement of the ankle and cervical spine (ARTHRITIS AND RHEUMATISM. 2009;60(12):3581-3581)
Adiponectin may contribute to synovitis and joint destruction in rheumatoid arthritis by stimulating vascular endothelial growth factor, matrix metalloproteinase-1, and matrix metalloproteinase-13 expression in fibroblast-like synoviocytes more than proinflammatory mediators. (Arthritis Res & Thr. 2009;11(61):00-00)
The use of etanercept in a patient with disseminated tuberculosis (Rheumatology international. 2009;29(0):1377-1380)
다운증후군 환자에서 병발한 재발성 다발연골염과 괴저성 농피증 1예 (대한내과학회지. 2009;76(5):632-636)
Mizoribine may suppress bone erosion in patients with rheumatoid arthritis by inhibiting osteoclastogenesis (EUROPEAN JOURNAL OF PHARMACOLOGY. 2009;605(0):46-48)
Song R, Lee S, Lee SH. Progressive sacroiliitis due to accessory sacroiliac joint mimicking ankylosing spondylitis: A case report. Medicine (Baltimore). 2019 Apr;98(16):e15324.
Jung SW, Choi YY, Choi IS, Kim S, Jeong KH, Song R, Lee SH, Yang HI,Hong SJ, Lee YA. Hypocomplementemic Urticarial Vasculitis Syndrome with Membranous Nephropathy: Case Report. J Korean Med Sci. 2017 Dec;32(12):2064-2068.
Song R, Chung SW, Lee SH.RadiographicEvidenceofHipJointRecoveryin Patients with Ankylosing Spondylitis after Treatment with Anti-tumor Necrosis Factor Agents: A Case Series. J Rheumatol. 2017 Nov;44(11):1759-1760. doi:10.3899/jrheum.161401. PubMed PMID: 29093078.
Hwang JJ, Ahn J, Kim KP, Choi HI, Choi JY, Song R, Lee YA, LeeS H, HongSJ, Yang HI. Henoch-Schönlein Purpura With Muscle Involvement, Presenting as Myositis. J Clin Rheumatol. 2017 Jan;23(1):60-62.
Lee YH, Kim EY, Jeong da W, Kim YG, Lee SH, SongR, YangHI, LimSJ, MoonJY, Lee SH. Complete Remission of Nephrotic Syndrome Without Resolution of Amyloid Deposit After Anti-Tumor Necrosis Factor α Therapy in a Patient With Ankylosing Spondylitis. J Clin Rheumatol. 2016 Mar;22(2):86-8.
Kim KS, You JS, Kim JY, Chang KJ, Yoo MC, Song R, Lee YA, LeeSH, HongSJ, Yang HI. Taurine ameliorates hypercholesterolemia but not obesity in rats fed a lard-based, high-fat diet. Adv Exp Med Biol. 2015;803:271-8. doi: 10.1007/978-3-319-15126-7_22. PubMed PMID: 25833504.
Kim KS, Lee YA, Ji HI, Song R, Kim JY, LeeSH,HongSJ,YooMC,YangHI. Increased expression of endocan in arthritic synovial tissues: effects of adiponectin on the expression of endocan in fibroblast-like synoviocytes. Mol Med Rep. 2015 Apr;11(4):2695-702. doi: 10.3892/mmr.2014.3057. PubMed PMID: 25483913.
Lee YA, Ji HI, LeeSH,HongSJ,YangHI,ChulYooM,KimKS.Theroleof adiponectin in the production of IL-6, IL-8, VEGF and MMPs in human endothelial cells and osteoblasts: implications for arthritic joints. Exp Mol Med. 2014 Jan 17;46:e72. doi: 10.1038/emm.2013.141. PubMed PMID: 24434628; PubMed Central
PMCID: PMC3909890.
Kim KS, Ji HI, Chung H, Kim C, LeeSH,LeeYA,YangHI,YooMC,HongSJ. Taurine chloramine modulates the expression of adipokines through inhibition of the STAT-3 signaling pathway in differentiated human adipocytes. Amino Acids. 2013 Dec;45(6):1415-22. doi: 10.1007/s00726-013-1612-z. PubMed PMID: 24178768.
Ji HI, LeeSH,SongR,YangHI,LeeYA,HongSJ,KimS,ParkYB,LeeSK,Yoo MC, Kim KS. Serum level of osteopontin as an inflammatory marker does not indicate disease activity or responsiveness to therapeutic treatments in patients with rheumatoid arthritis. Clin Rheumatol. 2014 Mar;33(3):397-402. doi:
10.1007/s10067-013-2375-3. PubMed PMID: 23995733.
Ko WJ, Kim KY, Kim SM, Hong SJ, LeeSH,SongR,YangHI,LeeYA.A case of myotonic dystrophy with electrolyte imbalance. J Korean Med Sci. 2013 Jul;28(7):1111-3. doi: 10.3346/jkms.2013.28.7.1111. PubMed PMID: 23853500; PubMed Central PMCID: PMC3708088.
Kim KS, Choi HM, Ji HI, Kim C, Kim JY, Song R, Kim SM, Lee YA, LeeSH,Yang HI, Yoo MC, Hong SJ. Effect of taurine chloramine on differentiation of human preadipocytes into adipocytes. Adv Exp Med Biol. 2013;775:247-57. doi: 10.1007/978-1-4614-6130-2_21. PubMed PMID: 23392940.
Lee SH, Lee EJ, Chung SW, Song R, Moon JY, LeeSH,LimSJ,LeeYA,HongSJ, Yang HI. Renal involvement in ankylosing spondylitis: prevalence, pathology, response to TNF-a blocker. Rheumatol Int. 2013 Jul;33(7):1689-92. doi: 10.1007/s00296-012-2624-9. PubMed PMID: 23269570.
Hwang HJ, Kim JI, Lee SH, Park CB, Sohn IS. Full-blown cardiac manifestations in ankylosing spondylitis. Echocardiography. 33(11):1785-1787 2016 Nov
Kim HW, Kwon SR, Jung KH, Kim SK, Baek HJ, Seo MR, Bang SY, Lee HS, Suh CH, Jung JY, Son CN, Shim SC, Lee SH, Lee SG, Lee YA, Lee EY, Kim TH, Kim YG; Safety of Resuming Tumor Necrosis Factor Inhibitors in Ankylosing Spondylitis Patients Concomitant with the Treatment of Active Tuberculosis: A Retrospective Nationwide Registry of the Korean Society of Spondyloarthritis Research. PLoS One 11(4) 2016 Apr
Won KY, Park SY, Lee SH Subcutaneous Sarcoidosis Mimicking Cellulitis. J Rheumatol. 43(3):674-5. 2016 Mar
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