Inhibition of Drp1 Ameliorates Synaptic Depression, Aβ Deposition, and Cognitive Impairment in an Alzheimer's Disease Model.
The anti-ALS drug riluzole attenuates pericyte loss in the diabetic retinopathy of streptozotocin-treated mice.
Ursodeoxycholic Acid Attenuates Endoplasmic Reticulum Stress-Related Retinal Pericyte Loss in Streptozotocin-Induced Diabetic Mice.
A novel mechanism for the pyruvate protection against zinc-induced cytotoxicity: mediation by the chelating effect of citrate and isocitrate.
Efficacy and safety of aflibercept in in vitro and in vivo models of retinoblastoma.
Inhibition of EHMT2/G9a epigenetically increases the transcription of Beclin-1 via an increase in ROS and activation of NF-κB.
Amyloid Beta-Weighted Cortical Thickness: A New Imaging Biomarker in Alzheimer's Disease.
Anti-angiogenic effect of metformin in mouse oxygen-induced retinopathy is mediated by reducing levels of the vascular endothelial growth factor receptor Flk-1.
Heterogeneous nuclear ribonucleoprotein A1 post-transcriptionally regulates Drp1 expression in neuroblastoma cells.
Indomethacin preconditioning induces ischemic tolerance by modifying zinc availability in the brain.
Metallothionein-3 modulates the amyloid β endocytosis of astrocytes through its effects on actin polymerization.
Trans-synaptic zinc mobilization improves social interaction in two mouse models of autism through NMDAR activation.
Exome array study did not identify novel variants in Alzheimer's disease.
Raloxifene induces autophagy-dependent cell death in breast cancer cells via the activation of AMP-activated protein kinase.
Suppression of Cpn10 increases mitochondrial fission and dysfunction in neuroblastoma cells.
Isolated Buccofacial Apraxia Subsequent to a Left Ventral Premotor Cortex Infarction.
Methallothionein-3 contributes to vascular endothelial growth factor induction in a mouse model of choroidal neovascularization.
Tissue plasminogen activator arrests Alzheimer's disease pathogenesis.
Alteration of the Cerebral Zinc Pool in a Mouse Model of Alzheimer Disease.
Association of GWAS Top Hits With Late-onset Alzheimer Disease in Korean Population.
Induction of autophagy and cell death by tamoxifen in cultured retinal pigment epithelial and photoreceptor cells.
Neuroprotection by urokinase plasminogen activator in the hippocampus
The neurosteroids, allopregnanolone and progesterone, induce autophagy in cultured astrocytes.
Clioquinol induces autophagy in cultured astrocytes and neurons by acting as a zinc ionophore.
Dependence of the histofluorescently reactive zinc pool on zinc transporter-3 in the normal brain.
Obesity and downregulated hypothalamic leptin receptors in male metallothionein-3-null mice.
Preferential inhibition of frontal-to-parietal feedback connectivity is a neurophysiologic correlate of general anesthesia in surgical patients.
The neurophysiology and pathology of brain zinc.
The role of zinc metallothionein-3 (ZnMT3) in EGF-induced c-Abl activation and actin polymerization in cultured astrocytes.
Zinc-triggered induction of tissue plasminogen activator by brain-derived neurotrophic factor and metalloproteinases
Apolipoprotein E ablation decreases synaptic vesicular zinc in the brain.
Chloroquine induces lysosomal dilatation, arrested autophagy and cell death in cultured ARPE-19 cells.
Induction of lysosomal dilatation, arrested autophagy, and cell death by chloroquine in cultured ARPE-19 cells.
Metallothionein-3 regulates lysosomal function in cultured astrocytes under both normal and oxidative conditions.
Zinc(II) ion mediates tamoxifen-induced autophagy and cell death in MCF-7 breast cancer cell line.
Age and body weight adjusted warfarin initiation program for ischaemic stroke patients.
Cytosolic labile zinc accumulation in degenerating dopaminergic neurons of mouse brain after MPTP treatment.
Endogenous Zinc Mediates Apoptotic Programmed Cell Death in the Developing Brain.
Inflammatory and Hemostatic Biomarkers Associated With Early Recurrent Ischemic Lesions in Acute Ischemic Stroke.
Oxidative injury triggers autophagy in astrocytes: The role of endogenous zinc.
Evidence that the ZNT3 protein controls the total amount of elemental zinc in synaptic vesicles.
Inhibitory effect of bevacizumab on the angiogenesis and growth of retinoblastoma.
Undernutrition as a Predictor of Poor Clinical Outcomes in Acute Ischemic Stroke Patients
Zinc and 4-hydroxy-2-nonenal mediate lysosomal membrane permeabilization induced by H2O2 in cultured hippocampal neurons.
Copper activates TrkB in cortical neurons in a metalloproteinase-dependent manner
Early recurrent ischemic lesions on diffusion-weighted imaging in symptomatic intracranial atherosclerosis
Early recurrent ischemic lesions on diffusion-weighted imaging in symptomatic intracranial atherosclerosis.
Insulin increases retinal hemorrhage in mild oxygen-induced retinopathy in the rat: inhibition by riluzole.
Non-proteolytic neurotrophic effects of tissue plasminogen activator on cultured mouse cerebrocortical neurons.
Pyruvate protects against kainate-induced epileptic brain damage in rats.
Systemic pyruvate administration markedly reduces infarcts and motor deficits in rat models of transient and permanent focal cerebral ischemia
Triamcinolone acetonide-mediated oxidative injury in retinal cell culture: comparison with dexamethasone.
Upregulation of tPA/plasminogen proteolytic system in the periphery of amyloid deposits in the Tg2576 mouse model of Alzheimer's disease.
A novel phospholipid derivative of indomethacin, DP-155 [mixture of 1-steroyl and 1-palmitoyl-2-{6-[1-(p- chlorobenzoyl)-5-methoxy-2- methyl-3-indolyl acetamido]hexanoyl}- sn-glycero-3-phosophatidyl [corrected] choline], shows superior safety and similar efficacy in reducing brain amyloid beta in an Alzheimer's disease model.
Cytosolic labile zinc: a marker for apoptosis in the developing rat brain
Synaptic release of zinc from brain slices: factors governing release, imaging, and accurate calculation of concentration
Riluzole inhibits VEGF-induced endothelial cell proliferation in vitro and hyperoxia-induced abnormal vessel formation in vivo.
Danthron inhibits the neurotoxicity induced by various compounds causing oxidative damages including ß-amyloid (25-35) in primary cortical cultures
Induction of pro-apoptotic calsenilin/DREAM/KChIP3 in Alzheimer's disease and cultured neurons after amyloid-b exposure
Infarct reduction in rats following intraventricular administration of either tissue plasminogen activator (tPA) or its non-protease mutant S478A-tPA
uronal zinc exchange with the blood vessel wall promotes cerebral amyloid angiopathy in an animal model of Alzheimer's disease.
Protection by pyruvate of rat retinal cells against zinc toxicity in vitro, and pressure- induced ischemia in vivo
induction and NMDA receptor-dependent neuronal death by neurotrophin-4/5 in cortical cell culture
Protection by pyrovate of rat retinal cells against zinc toxicity in vitro, and pressure-induced isahemia in vivo
Co-inguction of p75NTR and the associated death executor NADE in degenerating hippocampal netrons after kainate-induced seizures in the rat
Design andbiological evaluation of novel antioxidants containing N-t-Butul-N-hydroxylaminophenyl moieties
Down-regulation of ARC contributes to vulnerability of hippocampal neurons to ischemia/hypoxia
Essential role of E2-25K/ Hip-2 in the neurotoxicity of amyloid-b in Alzheimer's disease.
Pyruvate ingibits zinc-mediated pancreatic isclet cell death and diabetes
TrkB mediates BDNF-induced potentiation of neuronal necrosis in cortical culture.
Zinc released from metallothionein-III may contribute to hippicampal CA1 and thalamic neuronal death following acute brain injurt
Augmentation by zinc of NMDA receptor-mediated sunaptic responses in CA1 of rat hippocampal slices: mediation by src family tyrosine kinases.
Contribution by synaptic zinc to the gender-disparate plaque formation in human Swedish mutant APP transgenic mice.
Depletion of intarcellular zinc from neurons by use of an extracellular chelator in vivo and in vitro
Roles of NADPH oxidase, neuronal nittric oxide synthase and poly (ADPribose) poly-merase in oxidative neuronal death by brain-derived neurotrophic factor and neurotrophins-4/5 in cortical culture.
The role for NADPH oxidase and neuronal nitric oxide synthase in zinc-induced poly(ADP-ri-bose) polymerase activation and cell death in cortical culture
BAPTA/AM, an intracellular calcium chelator, induces delayed necrosis by lipoxygenase-mediated free radicals in mouse cortical cultures
Depletion of intracellular zinc and copper with TPEN results in apoptosis of cultured human retinal pigment epithelial cells.
Depletion of intracellular zinc and copper with TPEN results in apoptosis of cultured human retinel pigment epithelial cells
Protection by zinc against transient cerebral ischemia in rats
A case of internal carotid artery dissection presenting with isolated hypoglossal nerve palsy
Accumulation of zinc in degenerating hippocampal neurons of znT3-null mice following seizures: Evidence against synaptic vesicle origin
Anti-oxidative neuroprotection by estrogens in mouse cortical culture
Co-induction of p75NTR-associated death executer(NADE) in neurons following zinc exposure in cortical culture or transient ischemia in rats
Depletion of intracellular zinc induces macromolecule synthesis-and caspase-dependent apoptosis of cultured retinal cells
Epidermal growth factor induces oxidative neuronal injury in cortical culture
Ethambutol-induced vacuolar changes and neuronal loss in rat retinal cell culture: mediation by endogenous zinc.
Induction and activation of NADPH oxidase in cultured neurons and astrocytes
Induction by synaptic zinc of heat shock protein-70 in hippocampus after kainate seizures
Protein synthesis-dependent but Bcl-2-independent cytochrome C release in zinc depletion-induced neuronal apoptosis
Zinc as a paracrine effector in pancreatic islet cell death
Zn2+: Novel ionic mediator of neural injury in brain disease
Anti-oxidative and pro-apoptotic effects of riluzole in cortical cultures
High vulnerability of GABA-immunoreactive neurons to kainate in rat retinal cultures: correlation with the kainate-stimulated cobalt uptake.
Histochemically reactive zinc in plaques of the swedish mutant app transgenic mice
Induction of an immediate early gene egr-1 in cultured cortical neurons: its role in neuronal death
Insulin-induced oxidative neuronal injury in cortical culture: Mediation by the induced NMDA receptor
Ionomycin induces either apoptosis or necrosis in cortical culture
Mediation by membrane protein kinase C of zinc-induced oxidative neuronal injury in mouse cortical cultures
N-methyl-D-aspartate receptor antagonists induce neuronal apoptosis in cortical culture
Non-proteolytic neuroprotection by human recombinant tissue plasminogen activator
Presenilin-1 mediates PKC-dependent secretase derived APP secretion and MAPK activation in PS1 transfected HEK 293 cell
Prevention of neuronal apoptosis by phorbol ester-induced activation of protein kinase: C Blockade of p38 mitogen-activated protein kinase
Protective effects of asiaticoside derivatives against beta-amyloid neurotoxicity
Vertebrobasilar artery territory infarction as an initial manifestation of systemic lupus erythematosus
Zinc-induced cortical neuronal death with features of apoptosis and necrosis: Mediation by free radicals
Zn2+ entry produces oxidative neuronal necrosis in cortical cell cultures
b-Amyloid-induced changes of sensory transmission in the SI cortex of anesthesized rats
Depletion of intracellular zinc induces protein synthesis-dependent neuronal apoptosis in mouse cortical cultures
Medial medullary infarction with restricted sensory symptom
Zinc and brain injury
Measurement of intracellular free zinc in living cortical neurons: routes of entry
Slowly-triggered excitotoxicity occurs by necrosis in cortical culture
NADPH-diaphorase-containing striatal or cortical neurons are resistant to apoptosis
The Role of Zinc in Selective Neuronal Death After Transient Global Cerebral Ischemia
The role of zinc in selection neuronal death after transient global ischemia
Adult-Onset Hallervorden-Spatz disease(HBS) 에서의 proton nuclear MR spectroscopy(1H-MRS)소견