Dr. 이형근  
						Dr. Lee Hyeong Geun 					 
										
			
					
							
					
					
					
									
										
					
				 
				
			 
						
			
					
							
					학력 
					1988-1994년 연세대학교 의학학사
 1997-1999년 연세대학교 의학석사
 2003-2006년 연세대학교 의학박사 
				 
			
				
				
					경력 
					1994  ~  1995년      연세대학교  세브란스병원  인턴
 1995  ~  1999년      연세대학교  세브란스병원  안과전공의
 2000  ~  2002년      국군  수도병원  안과  군의관  및  과장
 2002  ~  2004년      연세대학교  의과대학  안과학  교실  임상강사
 2004  ~  2005년      연세대학교  의과대학  안과학  교실  전임강사
 2005  ~  2009년      연세대학교  의과대학  안과학  교실  조교수
 2008  ~  2009년      Harvard  Medical  School,  MEEI&SERI,  visiting  scholar
 2010  ~  2014년      연세대학교  의과대학  안과학  교실  부교수
 2015  ~    현재        연세대학교  의과대학  안과학  교실  교수
 2015  ~    현재        연세대학교  약학대학  겸무교수
 2018                       NIIOS  Clinic,  Rotterdam,  Netherland:  DMEK  연수 
				 
					
				
				
					학회 
					1994 ~ 현재 대한의학회회원
 1999 ~ 현재 대한안과학회회원
 2011 ~ 현재 대한안과학회 전문의고시위원
 2015 ~ 현재 안과학교과서 편찬위원
 2012 ~ 2014 대한안과학회 학술위원
 2013 ~ 2015 대한안과학회지(Korean Journal of Ophthalmological Society) 편집위원
 2012 ~ 2013 한국콘택트렌즈학회 총무이사
 2014 ~ 2015 한국백내장굴절학회 총무이사
 2012 ~ 2015 한국외안부학회 학술이사
 2018 ~ 현재 한국외안부학회 학술이사 및 운영위원
 2016 ~ 현재 각막질환연구회 Council Member 및 운영위원
 2018 ~ 현재 한국백내장굴절학회 기획이사
 2018 ~ 현재 한국콘택트렌즈학회 감사
 (국외활동)
 Journal of Ocular Pharmacology and Therapeutics, Editorial Board
 <비 SCI급 국외논문편집위원 및 비공개학술단체>
 Korean Journal of Ophthalmology (KJO), Associate Editor
 Asia Dry Eye Society, Council member
 ARVO : Association for Research in Vision and Ophthalmology, Member
 ASCRS : American Society of Cataract and Refractive Surgery, Member
 ESCRS : European Society of Cataract and Refractive Surgery, Member
 APACRS : Asia Pacific Academy of Cataract and Refractive Surgery, Member
 AAI : American association of Immunology, Member
 BSI : British Society of Immunology, Member
 ICIS : International Cytokine & Interferon Society, Member
 (정부기관 및 지역활동)
 2005 ~ 현재 국립 식품약품안정청 (KFDA) 안과분야 재료 및 기구 자문의원
 2013 ~ 현재 공무원연금공단 연금지급 심의위원
 (주관연구자로서 정부기관 연구비 수혜)
 2010년 연구재단 기본연구 60,000,000/1년
 A study for determining differentiation process of VEGFR2+CD11b+ mononuclear cell and its role for angiogenesis.
 2010년 장기해외연수교수연구비 25,000,000
 건성안을 이용한 임파관형성 관련 인자 발굴 및 면역병리기전 연구
 2011년 연구재단 기본연구 180,000,000/3년
 다양한 in vivo mouse 각막모델을 이용한 임파관신생(Lymphangiogenesis)의 연구
 2012년 연구재단 중견연구사업, 핵심연구 600,000,000/3년
 Decoy receptor D6를 이용한 multichemokine trap의 제작과 동종이식 거부에 대한연구
 2013년 보건산업진흥원, 기후환경변화 대응전략연구 1,500,000,000/5년
 환경성안질환의 바이오마커 발굴과 케모카인 트랩에 기반한 치료제 개발
 2015년 연구재단 중견연구 핵심공동연구 600,000,000/3년
 난치성면역질환에서 tyrosine-O-sulfation을 이용한 SSP의 개발
 2017년 연구재단 나노소재기술개발사업 4,350,000,000/5년
 방수(aqueous humor) 액체생검을 이용한 뇌질환 바이오마커 탐색과 생체감응형 패턴화 하이드로젤 모듈 개발을 통한 마커 센싱 시스템 구축
 2018년 연구재단 중견연구 600,000,000/3년
 이식거부반응 억제를 위한 동계(syngeneic), 이종(Xenogeneic) 이식 면역반응과의 동시비교를 통한 동종(allogenic)이식 특이 마커의 도출과 이식거부에서의 역할 탐색
 2018년 보건산업진흥원 보건의료기술연구개발사업
 (수상 경력)
 2007년 범석장학재단 학술상 최우수상
 2007년 태준 최우수 안과연구상
 2009년 연세의대 연구업적 우수 교수상
 2010년 대한안과학회 추계학술대회 학술상
 2011년 대한안과학회 춘계학술대회 학술상
 2012년 연세의대 연구업적 우수 교수상
 2015년 대한안과학회 춘계학술대회 학술상
 2016년 대한의학회: 톱콘학술상
 2016년 대한안과학회 춘계학술대회 학술상
 2017년 대한안과학회 추게학술대회 학술상
 2018년 대한안과학회 춘계학술대회 학술상
 (국제 학회 초청 발표)
 2008년 Boston Angiogenesis Meeting, Boston, MA (2008.11.7) A novel tyrosine kinase mediated Hemangiogenesis.
 2010년 Kyoto International Cornea Society Meeting (2010, 12. 4)
 2012년 Kyoto University, Department of Ophthalmology, International Seminar Invited Speaker
 2014년 Asia Corneal Society, Taipei, Dec 10-12, for improving corneal allograft survival
 2014년 Asia Dry Eye Society meeting, Tokyo, Japan. Nov. 18-19,
 2016년 Japanese Ophthalmological Society, Sendai, Japan (4월 2일)
 Asia Dry Eye Society, Xiemen, China, November 14
 Asia Cornea Society, Seoul, Korea, Dec 9-11
 2017년 Keio University Dry Eye Symposium, Tokyo, January 27
 2017년 Association for Vision Research and Ophthalmology, USA
 2017년 Korean Ophthalmologists Association Symposium, Korea
 2017년 Asia Dry Eye Society, Osaka, Japan
 Korean Japan and China Ophthalmological Society, Seoul, Korea
 2018년 Asia Cornea Society, Qingdao, China
 (특허실적)
 특허명
 황산화된 더피 케모카인 수용체의 세포 외 도메인 1 변이체 및 이의 용도
 황산화된 D6 디코이 수용체의 세포 외 도메인 1 변이체 및 이의 용도
 멜록시캄을 포함하는 안구 건조증 치료용 약학 조성물
 니메술러드를 포함하는 안구 건조증 치료용 약학 조성물
 씨스-스틸벤을 포함하는 안구 건조증 치료용 약학 조성물
 이부프로펜을 포함하는 안구 건조증 치료용 약학 조성물
 3,5-다이-터트-부릴-4-하이드록시벤질리딘을 포함하는 안구 건조증 치료용 약학 조성물
 PGE2 합성 억제제를 포함하는 안구 통증 치료용 약학 조성물
 D6 디코이 수용체의 세포 외 도메인 1을 포함하는 항암용 약학 조성물
 PGE2 합성 억제제를 포함하는 안구 통증 치료용 약학 조성물
 황산화된 D6 디코이 수용체의 세포 외 도메인 1 변이체 및 이의 용도
 PGE2 합성 억제제를 포함하는 안구 통증 치료용 약학 조성물 
				 
		
		
						
					논문 
					
						1. Kay EP., Lee HK, Park KS, Lee SS. Indirect mitogenic effect of transforming growth factor-β on cell proliferation of subconjunctival fibroblasts. Invest Ophthalmol Vis Sci. 1998;39 (3): 481-6
 2. Seong GJ, Lee HK, Hong YJ. Effect of 0.005% latanoprost on optic nerve head and peripapillary retinal blood flow. Ophthalmologica 1999;213:355-359
 3. Lee HK, Kim JK, Kim EK, Kim GO, Lee IS. Phototherapeutic keratectomy with amniotic membrane for severe subepithelial fibrosis following excimer laser refractive surgery. J Cataract and Refractive Surg 2003;29:1430-1435. (First and Corresponding author)
 4. Lee HK, Koh IH, Choe CM, Kim CY, Seong GJ. Reproducibility of morphoscopic contrast sensitivity obtained with the visual capacity analyzer. J Cataract and Refractive Surg 2003;29:1776-1779
 5. Lee HK, Kim JK, Kim SS, Kim EK, Kim KO, Lee IS, Seong GJ. Effect of amniotic membrane after laser-assisted subepithelial keratectomy on epithelial healing: clinical and refractive outcomes. J Cataract Refract Surg. 2004 Feb;30(2):334-40.
 6. Kim JK, Kim SS, Lee HK, Lee IS, Seong GJ, Kim EK, Han SH. Laser in situ keratomileusis versus laser-assisted subepithelial keratectomy for the correction of high myopia. J Cataract Refract Surg. 2004 Jul;30(7):1405-11. (Corresponding Author)
 7. Lee HK, Kim CY, Kwon OW, Kim EK, Lee SC, Seong GJ, Kim SS. Removal of dense posterior capsule opacification after congenital cataract extraction using the transconjunctival sutureless vitrectomy system. J Cataract Refract Surg. 2004 Aug;30(8):1626-8.
 8. Lee JH, Lee HK, Kim JK, Chang JH, Kim SE, Kim EK, Seong GJ, Hong S. Expression of laminin-5 with amniotic membrane transplantation in excimer laser ablated rat corneas. J Cataract Refract Surg. 2004 Oct;30(10):2192-9. (Corresponding Author)
 9. Lee HK, Lee KS, Kim JK, Kim HC, Seo KR, Kim EK. Epithelial healing and clinical outcomes in excimer laser photorefractive surgery following three epithelial removal techniques: mechanical, alcohol, and excimer laser. Am J Ophthalmol. 2005 Jan;139(1):56-63.
 10. Lee HK, Lee KS, Kim HC, Lee SH, Kim EK. Nerve Growth Factor Concentration and Implications in Photorefractive Keratectomy vs Laser In Situ Keratomileusis. Am J Ophthalmol. 2005 Jun;139(6):965-71.
 11. Lee JH, Lee HK, Kim CY, Hong YJ, Choe CM, You TW, Seong GJ. Purified high-dose anthocyanoside oligomer administration improves nocturnal vision and clinical symptoms in myopia subjects. Br J Nutr. 2005;93:895-899.
 12. Lee JH, Rye IH, Kim EK, Lee JE, Hong SW, Lee HK. Induced expression of insulin-like growth factor-1 by amniotic membrane-conditioned medium in cultured human corneal epithelial cells. Invest Ophthalmolol Vis Sci 2006;47:864-872. (Corresponding Author)
 13. Lee HK, Lee JH, Kim M, Kariya Y, Miyazaki K, Kim EK. Insulin-like growth factor-1 (IGF-1) induces migration and expression of laminin-5 in cultured human corneal epithelial cells. Invest Ophthalmolol Vis Sci. 2006;47:873-82.
 14. Lee HK, Rye IH, Seo KY, Hong SW, Kim HC, Kim EK. Topical 0.1% Prednisolone lowers nerve growth factor expression in keratoconjunctivitis sicca patients. Ophthalmology 2006;113:198-205.
 15. Nam SM, Lee HK, Kim EK, Seo KY. Comparison of corneal thickness after the instillation of topical anesthetics: proparacaine versus oxybuprocaine. Cornea. 2006 Jan;25(1):51-4.
 16. Lee ES, Lee HK, Cristol SM, Kim SJ, Lee MI, Seo KY, Kim EK. Amniotic membrane as a biologic pressure patch for treating epithelial ingrowth under a damaged laser in situ keratomileusis flap. J Cataract Refract Surg. 2006 Jan;32(1):162-5.
 17. Seo KY, Lee HK, Kim EK, Lee JH. Expression of tumor necrosis factor alpha and matrix metalloproteinase-9 in surgically induced necrotizing scleritis. Ophthalmic Res. 2006;38(2):66-70.
 18. Hong S, Lee HK, Lee JB, Han SH. Recession-resection combined with intraoperative botulinum toxin A chemodenervation for exotropia following butotal ruptured of medial rectus muscle. Grafe’s Arch Clin Exp Ophthalmol. 2007;245:167-9.
 19. Lee HK, Choe CM, Ma KT, Kim EK. Measurement of contrast sensitivity and glare under mesopic and photopic conditions following wavefront-guided and conventional LASIK surgery. J Refract Surg. 2006;22:647-655.
 20. Lee SJ, Kim JK, Seo KY, Kim EK, Lee HK. Comparison of corneal nerve regeneration and sensitivity between LASIK and laser epithelial keratomileusis (LASEK). Am J Ophthalmol. 2006 Jun;141(6):1009-1015. (Corresponding Author)
 21. Chung SH, Roh MI, Park MS, Kong YT, Lee HK, Kim EK. Mycobacterium abscessus keratitis after LASIK with IntraLase femtosecond laser. Ophthalmologica. 2006;220(4):277-80
 22. Chung SH, Lee IS, Lee YG, Lee HK, Kim EK, Yoon G, Seo KY. Comparison of higher-order aberrations after wavefront-guided laser in situ keratomileusis and laser-assisted subepithelial keratectomy. J Cataract Refract Surg. 2006 May;32(5):779-84.
 23. Lee HK, Yoon JS, Kim SJ, Kim CY, Song H, Hwang KC, Lee JB, Lee JH Upregulation of TGF-beta-induced tissue transglutaminase expression by PI3K-Akt pathway activation in human subconjunctival fibroblasts.. Invest Ophthalmol Vis Sci 2007;48:1952-1958.
 24: Chung SH, Lee SJ, Lee HK, Seo KY, Kim EK. Changes in higher order aberrations and contrast sensitivity after implantation of a phakic artisan intraocular lens. Ophthalmologica. 2007;221(3):167-72.
 25: Lee JH, Chung SH, Stulting RD, Kim WC, Lee HK, Kim EK. Effects of corneal neovascularization on the manifestations of Avellino corneal dystrophy (granular corneal dystrophy type II). Cornea. 2006 Sep;25(8):914-8.
 26. Chung JL, Kim SW, Kim JH, Kim TI, Lee HK, Kim EK.A case of weill-marchesani syndrome with inversion of chromosome 15.Korean J Ophthalmol. 2007 Dec;21(4):255-60.
 27. Chung SH, Lee JH, Yoon JH, Lee HK, Seo KY. Multi-layered culture of primary human conjunctival epithelial cells producing MUC5AC. Exp Eye Res. 2007 Aug;85(2):226-33.
 28. Kim M, Lee YG, Seo KR, Kim EK, Lee HK. Comparison of higher-order aberrations between eyes with natural supervision and highly myopic eyes in Koreans. Korean J Ophthalmol. 2007 Jun;21(2):79-84. (Corresponding author)
 29. Park KS, Kim HC, Ahn CW, Kim JC, Lee HK. Serum and tear levels of nerve growth factors in diabetic retinopathy patients. Am J Ophthalmol 2008;145(3):432-7. (corresponding author)
 30. Chung SA, Kim JK, Kim EK, Lee HK. Effectiveness of cultured human keratinocyte flaps on epithelial healing and clinical outcomes after photorefractive keratetomy. J Refract Surg 2008 Oct;24(8):826-32. (corresponding author)
 31. Kim M, Kim JK, Lee HK. Corneal endothelial decompensation after iris claw type phakic intraocular lens implantation. J Cat Refract Surg 2008 34(3):517-519. (corresponding author)
 32. Lee JH, Kim M, Im YS, Choi WR, Byeon SH, Lee HK. NFAT5 induction and its role in hyperosmolar stressed human limbal epithelial cell. Invest Ophthalmol Vis Sci 2008:49(5):1827-35, (corresponding author)
 33. Chang EJ, Im YS, Kay EP, Kim JY, Lee JE, Lee HK. The role of nerve growth factor in hyperosmolar stress induced apoptosis. J Cell Physiol 2008;216(1):69-77. (corresponding author)
 34. Hong S, Lee SJ, Lee HK, Seong GJ, Han SH.Surgical management for large hypertropia and exotropia after disinsertion of inferior rectus muscle. Ophthalmic Surg Lasers Imaging. 2008 Nov-Dec;39(6):505-7.
 35. Chung SH, Kweon MN, Lee HK, Choi SI, Yang JY, Kim EK. Toll-like receptor 4 initiates an innate immune response to lipopolysaccharide in human conjunctival epithelial cells. Exp Eye Res. 2009 Jan;88(1):49-56.
 36. Ma KT, Kim SS, Seong GJ, Lee HK, Kim CY. Scleral fixation of a silicone plate haptic intraocular lens in a patient showing repeated pupillary intraocular lens capture. Ophthalmic Surg Lasers Imaging. 2008 Jul-Aug;39(4):335-8.
 37. Kim TI, Choi SI, Lee HK, Cho YJ, Kim EK. Mitomycin C induces apoptosis in cultured corneal fibroblasts derived from type II granular corneal dystrophy corneas. Mol Vis. 2008 Jun 30;14:1222-8.
 38. Hong S, Lee HK, Kim CY, Seong GJ. Identification and localization of alpha-synuclein in human cornea.Korean J Ophthalmol. 2008 Jun;22(2):145-6.
 39. Hong S, Choi JY, Lee HK, Seong GJ, Seo KY, Kim EK, Byeon SH. Expression of neurotrophic factors in human primary pterygeal tissue and selective TNF-alpha-induced stimulation of ciliary neurotrophic factor in pterygeal fibroblasts. Exp Toxicol Pathol. 2008 Sep;60(6):513-20.
 40. Kim M, Chung SH, Lee JH, Lee HK, Seo KY. Comparison of mini-flap technique and conjunctival autograft transplantation without mitomycin C in primary and recurrent pterygium. Ophthalmologica. 2008;222(4):265-71.
 41. Chauhan SK, Saban DR, Lee HK, Dana R. Levels of Foxp3 in regulatory T cells reflect their functional status in transplantation. J Immunol. 2009 Jan 1;182(1):148-53.
 42. Kim HC, Cho YJ, Ahn CW, Park KS, Kim JC, Nam JS, Im YS, Lee JE, Lee SC, Lee HK. Nerve growth factor and expression of its receptors in patients with diabetic neuropathy. Diabet Med. 2009 Dec;26(12):1228-34.
 43 Shim J, Park C, Lee HS, Park MS, Lim HT, Chauhan S, Dana R, Lee H, Lee HK. Change in Prostaglandin Expression Levels and Synthesizing Activities in Dry Eye Disease. Ophthalmology 2012:119:2211-9
 44. Lee HK, Jung SA, Lee SJ, Chee HY, Sohn YH, Lee JH. Transduction of PTEN proteins using the tat domain modulates TGF-β1-mediated signaling pathways and transdifferentiation in subconjunctival fibroblasts. Invest Ophthalmol Vis Sci. 2012 Jan 25;53(1):379-86.
 45. Lee JH, Kim JW, Im YS, Seong GJ, Lee HK. Cyclosporine A induces nerve growth factor expression via activation of MAPK p38 and NFAT5. Cornea. 2011 Oct;30 Suppl 1:S19-24. (Corresponding author)
 46. Chauhan SK, Jin Y, Goyal S, Lee HS, Fuchsluger TA, Lee HK, Dana R. A novel pro-lymphangiogenic function for Th17/IL-17. Blood. 2011 Oct 27;118(17):4630-4.
 47. Lee HK, Chauhan SK, Kay EP, Dana R. Flt-1 regulates vascular endothelial cell migration via a protein tyrosine kinase-7-dependent pathway. Blood. 2011 May 26;117(21):5762-71.
 48. Chung ES, Lee KH, Kim M, Chang EJ, Chung TY, Kim EK, Lee HK. Expression of neurotrophic factors and their receptors in keratoconic cornea. Curr Eye Res. 2013 Jul;38(7):743-50 (Corresponding author)
 49. Rim TH, Shim J, Kim DW, Lee HK. Author reply: To PMID 22858125. Ophthalmology. 2013 Sep;120(9):e59. (Corresponding author)
 50. Ji YW, Byun YJ, Choi W, Jeong E, Kim JS, Noh H, Kim ES, Song YJ, Park SK, Lee HK. Neutralization of ocular surface TNF-α reduces ocular surface and lacrimal gland inflammation induced by in vivo dry eye. Invest Ophthalmol Vis Sci. 2013 Nov 15;54(12):7557-66 (Corresponding author)
 51. Kim J, Lee KA, Kim EK, Lee HK. A Korean patient with lattice corneal dystrophy type IV with Leu527Arg mutation in the TGFBI gene. Korean J Ophthalmol. 2014 Feb;28(1):83-5. (Corresponding author)
 52. Ryu IH, Han J, Lee HK, Kim JK, Han SH. Changes in the accommodation-convergence relationship after the Artisan phakic intraocular lens implantation for myopic patients. Korean J Ophthalmol. 2014 Apr;28(2):150-4
 53. Eom Y, Choi KE, Kang SY, Lee HK, Kim HM, Song JS. Comparison of meibomian gland loss and expressed meibum grade between the upper and lower eyelids in patients with obstructive meibomian gland dysfunction. Cornea. 2014 May;33(5):448-52.
 54. Hyon JY, Kim HM, Lee D, Chung ES, Song JS, Choi CY, Lee J; Korean Corneal Disease Study Group. Korean guidelines for the diagnosis and management of dry eye: development and validation of clinical efficacy. Korean J Ophthalmol. 2014 Jun;28(3):197-206
 55. Seo Y, Ji YW, Lee SM, Shim J, Noh H, Yeo A, Park C, Park MS, Chang EJ, Lee HK.
 Activation of HIF-1α (hypoxia inducible factor-1α) prevents dry eye-induced acinar cell death in the lacrimal gland. Cell Death Dis. 2014 Jun 26;5:e1309. (Corresponding author)
 56. Chung YH, Choi B, Song DH, Song Y, Kang SW, Yoon SY, Kim SW, Lee HK, Chang EJ. Interleukin-1β promotes the LC3-mediated secretory function of osteoclast precursors by stimulating the Ca²?-dependent activation of ERK. Int J Biochem Cell Biol. 2014 Sep;54:198-207.
 57. Um SB, Kim NH, Lee HK, Song JS, Kim HC. Spatial epidemiology of dry eye disease: findings from South Korea. Int J Health Geogr. 2014 Aug 15;13:31
 58. Han J, Hong S, Lee S, Kim JK, Lee HK, Han SH. Changes in fusional vergence amplitudes after laser refractive surgery for moderate myopia. J Cataract Refract Surg. 2014 Oct;40(10):1670-5
 59. Ji YW, Seo Y, Choi W, Yeo A, Noh H, Kim EK, Lee HK. Dry eye-induced CCR7+CD11b+ cell lymph node homing is induced by COX-2 activities. Invest Ophthalmol Vis Sci. 2014 Sep 25;55(10):6829-38.
 60. Ji YW, Cho YJ, Lee CH, Hong SH, Chung DY, Kim EK, Lee HK. Comparison of surface roughness and bacterial adhesion between cosmetic contact lenses and conventional contact lenses. Eye Contact Lens. 2015 Jan;41(1):25-33.
 61. Choi W, Byun YJ, Jung E, Noh H, Hajrasouliha AR, Sadrai Z, Chang E, Lee JH, Lee HK. Chemokine decoy receptor D6 mimicking trap (D6MT) prevents allosensitization and immune rejection in murine corneal allograft model. J Leukoc Biol. 2015 Feb;97(2):413-24.
 62. Seo Y, Kim MK, Lee JH, Chang EJ, Kim EK, Lee HK. Expression of Lymphangiogenic Markers in Rejected Human Corneal Buttons after Penetrating Keratoplasty. Curr Eye Res. 2015 Sep;40(9):902-12
 63. Eom Y, Lee JS, Keun Lee H, Myung Kim H, Suk Song J. Comparison of conjunctival staining between lissamine green and yellow filtered fluorescein sodium. Can J Ophthalmol. 2015 Aug;50(4):273-7
 64. Chauhan SK, Lee HK, Lee HS, Park EY, Jeong E, Dana R. PTK7+ Mononuclear Cells Express VEGFR2 and Contribute to Vascular Stabilization by Upregulating Angiopoietin-1. Arterioscler Thromb Vasc Biol. 2015 Jul;35(7):1606-15 (co-corresponding author)
 65. Ji Hwan Min, Chul Hee Lee, Yong Woo Ji, Areum Yeo, Hyemi Noh, Insil Song, Eung Kweon Kim, Hyung Keun Lee. Activation of Dll4/Notch signaling and Hypoxia-inducible factor-1 alpha facilitates lymphangiogenesis in lacrimal glands in dry eye. PLoS One (In press, corresponding author)
 66. Jeon HS, Hyon JY, Kim MK, Chung TY, Yoon KC, Kim JY, Na KS, Kim HJ, Kim TI, Lee JS, Lee HK, Song JS Efficacy and safety of immunosuppressive agents in the treatment of necrotising scleritis: a retrospective, multicentre study in Korea. Br J Ophthalmol. 2015 Nov 23.
 67. Eom Y, Song JS, Lee DY, Kim MK, Kang BR, Heo JH, Lee HK, Kim HM. Effect of Titanium Dioxide Nanoparticle Exposure on the Ocular Surface: An Animal Study. Ocul Surf. 2016 Jan 14.
 68. Choi EY, Kang HG, Kim TI, Kim EK, Lee HK. Effect of postoperative administration of nonsteroidal antiinflammatory drugs and steroids on the conformational changes in wound healing after cataract surgery. J Cataract Refract Surg. 2016 Dec;42(12):1804-1813. doi: 10.1016/j.jcrs.2016.10.015.
 69. Min JH, Lee CH, Ji YW, Yeo AR, Noh HM, Song IS, Kim EK, Lee HK. Activation of Dll4/Notch Signaling and Hypoxia-Inducible Factor-1 Alpha Facilitates Lymphangiogenesis in Lacrimal Glands in Dry Eye. PLoS ONE. 2016 Feb;11(2):e0147846. doi: 10.1371/journal.pone.0147846.
 70. Choi WR, Noh HM, Yeo AR, Jang HM, Ahn HK, Song YJ, Lee HK. The Effect of TNF-α Blocker HL036337 and Its Best Concentration to Inhibit Dry Eye Inflammation. KJO. 2016 Aug;30(4):302-308. doi: 10.3341/kjo.2016.30.4.302.
 71. Choi WR, Ji YW, Ham HY, Yeo AR, Noh HM, Jin SE, Song JS, Kim HC, Kim EK, Lee HK. Gr-1(int)CD11b(+) myeloid-derived suppressor cells accumulate in corneal allograft and improve corneal allograft survival. J Leukoc Biol. 2016 Dec;100(6):1453-1463. doi: 10.1189/jlb.5A1115-508RR.
 72. Ji YW, Mittal SK, Hwang HS, Chang EJ, Lee JH, Seo Y, Yeo A, Noh H, Lee HS, Chauhan SK, Lee HK. Lacrimal gland-derived IL-22 regulates IL-17-mediated ocular mucosal inflammation. Mucosal Immunol. 2017 Sep;10(5):1202-1210.
 73. Jung JH, Ji YW, Hwang HS, Oh JW, Kim HC, Lee HK, Kim KP. Proteomic analysis of human lacrimal and tear fluid in dry eye disease. Sci Rep. 2017 Oct 17;7(1):13363. doi: 10.1038/s41598-017-13817-y.
 74. Choi EY, Kang HG, Lee CH, Yeo A, Noh HM, Gu N, Kim MJ, Song JS, Kim HC, Lee HK. Langerhans cells prevent subbasal nerve damage and upregulate neurotrophic factors in dry eye disease. PLoS One. 2017 Apr 25;12(4):e0176153. doi: 10.1371/journal.pone.0176153.
 75. Lee S, Jung G, Lee HK. Comparison of Contact Lens Corrected Quality of Vision and Life of Keratoconus and Myopic Patients. Korean J Ophthalmol. 2017 Dec;31(6):489-496. doi: 10.3341/kjo.2016.0107.
 76. Eom Y, Han JY, Kang B, Hwang HS, Lee HK, Kim HM, Song JS. Meibomian Glands and Ocular Surface Changes After Closure of Meibomian Gland Orifices in Rabbits. Cornea. 2018 Feb;37(2):218-226. doi: 10.1097/ICO.0000000000001460.
 77. Jeon DH, Yeom H, Yang J, Song JS, Lee HK, Kim HC. Are Serum Vitamin D Levels Associated With Dry Eye Disease? Results From the Study Group for Environmental Eye Disease. J Prev Med Public Health. 2017 Nov;50(6):369-376. doi: 10.3961/jpmph.17.089.
 78. Park YR, Song JS, Choi CY, Yoon KC, Lee HK, Kim HS. A Randomized Multicenter Study Comparing 0.1%, 0.15%, and 0.3% Sodium Hyaluronate with 0.05% Cyclosporine in the Treatment of Dry Eye. J Ocul Pharmacol Ther. 2017 Mar;33(2):66-72. 10.1089/jop.2016.0086.
 79. Ji YW, Kim MS, Kang SY, Reinstein DZ, Archer TJ, Choi JY, Kim EK, Lee HK, Seo KY, Kim TI. Lower Laser Energy Levels Lead to Better Visual Recovery After Small-Incision Lenticule Extraction: Prospective Randomized Clinical Trial. Am J Ophthalmol. 2017 Jul;179():159-170. 10.1016/j.ajo.2017.05.005.
 80. Ji YW, Kim MS, Kang SY, Reinstein DZ, Archer TJ, Choi JY, Kim EK, Lee HK, Seo KY, Kim TI. J Refract Surg Effect of Lowering Laser Energy on the Surface Roughness of Human Corneal Lenticules in SMILE. 2017 Sep;33(9):617-624. 10.3928/1081597X-20170620-02.
 81. Jeon DH, Yeom H, Yang J, Song JS, Lee HK, Kim HC. Are Serum Vitamin D Levels Associated With Dry Eye Disease? Results From the Study Group for Environmental Eye Disease. J Prev Med Public Health. 2017 Nov;50(6):369-376. doi: 10.3961/jpmph.17.089.
 82. Ahn S, Eom Y, Kang B, Park J, Lee HK, Kim HM, Song JS. Effects of Menthol-Containing Artificial Tears on Tear Stimulation and Ocular Surface Integrity in Normal and Dry Eye Rat Models. Curr Eye Res. 2018 May;43(5):580-587. doi: 0.1080/02713683.2018.1434895. Epub 2018 Feb 8
 83. Ji YW, Lee JL, Kang HG, Gu N, Byun H, Yeo A, Noh H, Kim S, Choi EY, Song JS, Lee HK. Corneal lymphangiogenesis facilitates ocular surface inflammation and cell trafficking in dry eye disease. Ocul Surf. 2018 Mar 27. pii: S1542-0124(17)30188-X. doi: 10.1016/j.jtos.2018.03.008. [Epub ahead of print]
 84. Eom Y, Han JY, Kang B, Hwang HS, Lee HK, Kim HM, Song JS. Meibomian Glands and Ocular Surface Changes After Closure of Meibomian Gland Orifices in Rabbits. Cornea. 2018 Feb;37(2):218-226. doi: 10.1097/ICO.0000000000001460.
 Phototherapeutic keratectomy with amniotic membrane for severe subepithelial fibrosis following excimer laser refractive surgery
 JOURNAL OF CATARACT AND REFRACTIVE SURGERY 29/7 :1430-1435,2003
 Reproducibility of morphoscopic contrast sensitivity testing with the Visual Capacity Analyzer
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 Expression of laminin-5 with amniotic membrane transplantation in excimer laser ablated rat corneas
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 Purified high-dose anthocyanoside oligomer administration improves nocturnal vision and clinical symptoms in myopia subjects
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 Comparison of higher-order aberrations after wavefront-guided laser in situ keratomileusis and laser-assisted subepithelial keratectomy
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 Comparison of corneal thickness after the instillation of topical anesthetics - Proparacaine versus oxybuprocaine
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 Expression of tumor necrosis factor alpha and matrix metalloproteinase-9 in surgically induced necrotizing scleritis
 OPHTHALMIC RESEARCH 38/2 :66-70,2006
 Comparison of Corneal Nerve Regeneration and Sensitivity Between LASIK and Laser Epithelial Keratomileusis (LASEK)
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 Measurement of contrast sensitivity and glare under mesopic and photopic conditions following wavefront-guided and conventional LASIK surgery
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 Amniotic membrane as a biologic pressure patch for treating epithelial ingrowth under a damaged laser in situ keratomileusis flap
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 Multi-layered culture of primary human conjunctival epithelial cells producing MUC5AC
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 Changes in higher order aberrations and contrast sensitivity after implantation of a phakic Artisan intraocular lens
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 Recession-resection combined with intraoperative botulinum toxin A chemodenervation for exotropia following subtotal ruptured of medial rectus muscle
 GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY 245/ :167-169,2007
 A Case of Weill-Marchesani Syndrome with Inversion of Chromosome 15
 Korean Journal of Ophthalmology 21/4 :255-260,2007
 Comparison of higher-order aberrations between eyes with natural supervision and highly myopic eyes in Koreans
 Korean Journal of Ophthalmology 21/2 :79-84,2007
 Scleral fixation of a silicone plate haptic intraocular lens in a patient showing repeated pupillary intraocular lens capture
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 Mitomycin C induces apoptosis in cultured corneal fibroblasts derived from type II granular corneal dystrophy corneas
 Molecular Vision 14/ :1222-1228,2008
 Identification and Localization of AlphaSynuclein in Human Cornea
 Korean Journal of Ophthalmology 22/2 :145-146,2008
 Expression of neurotrophic factors in human primary pterygeal tissue and selective TNF-α-induced stimulation of ciliary neurotrophic factor in pterygeal fibroblasts
 Experimental And Toxicologic Pathology 60/6 :513-520,2008
 The role of nerve growth factor in hyperosmolar stress induced apoptosis
 Journal Of Cellular Physiology 216/ :69-77,2008
 Serum and Tear Levels of Nerve Growth Factor in Diabetic Retinopathy Patients
 American Journal Of Ophthalmology 145/ :432-437,2008
 Comparison of mini-flap technique and conjunctival autograft transplantation without mitomycin C in primary and recurrent pterygium
 Ophthalmologica 222/ :265-271,2008
 Phacoemulsification using iris hooks and scleral fixation of the intraocular lens in patients with secondary glaucoma associated with lens subluxation
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 Effectiveness of cultured human keratinocyte onlays on epithelial healing and clinical outcome after photorefractive keratectomy
 Journal Of Refractive Surgery 24/ :826-832,2008
 Surgical management for large hypertropia and exotropia after disinsertion of inferior rectus muscle
 Ophthalmic Surgery Lasers & Imaging 39/6 :505-507,2008
 난시교정용 홍채고정 유수정체 안내렌즈의 6개월 임상성적
 대한안과학회지 49/1 :48-56,2008
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 Toll-like receptor 4 initiates an innate immune response to lipopolysaccharide in human conjunctival epithelial cells
 Experimental Eye Research 88/ :49-56,2009
 Decreased Catalase Expression and Increased Susceptibility to Oxidative Stress in Primary Cultured Corneal Fibroblasts from Patients with Granular Corneal Dystrophy Type II
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 Nerve growth factor and expression of its receptors in patients with diabetic neuropathy
 Diabetic Medicine 26/12 :1228-1234,2009
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 Intraocular Lens Power Calculations for Cataract Surgery After Phototherapeutic Keratectomy in Granular Corneal Dystrophy Type 2
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 Change in Prostaglandin Expression Levels and Synthesizing Activities in Dry Eye Disease
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 Comparison of Meibomian Gland Loss and Expressed Meibum Grade Between the Upper and Lower Eyelids in Patients With Obstructive Meibomian Gland Dysfunction
 CORNEA 33/5 :448-452,2014
 Changes in the accommodation-convergence relationship after the Artisan phakic intraocular lens implantation for myopic patients
 Korean Journal of Ophthalmology 28/2 :150-154,2014
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 PLOS ONE 11/2 :e0147846-,2016
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 건성안 진단에서 눈물띠 측정 스트립의 유효성
 대한안과학회지 57/10 :1,521-1,526,2016
 Efficacy and safety of immunosuppressive agents in the treatment of necrotising scleritis: a retrospective, multicentre study in Korea
 BRITISH JOURNAL OF OPHTHALMOLOGY 100/8 :1,066-1,070,2016
 Langerhans cells prevent subbasal nerve damage and upregulate neurotrophic factors in dry eye disease
 PLOS ONE 12/4 :e0176153-,2017
 Lower Laser Energy Levels Lead to Better Visual Recovery After Small-Incision Lenticule Extraction: Prospective Randomized Clinical Trial.
 AMERICAN JOURNAL OF OPHTHALMOLOGY 179/ :159-170,2017
 Effect of Lowering Laser Energy on the Surface Roughness of Human Corneal Lenticules in SMILE
 JOURNAL OF REFRACTIVE SURGERY 33/9 :617-624,2017
 Lacrimal gland-derived IL-22 regulates IL-17-mediated ocular mucosal inflammation
 MUCOSAL IMMUNOLOGY 10/5 :1,202-1,210,2017
 A Randomized Multicenter Study Comparing 0.1%, 0.15%, and 0.3% Sodium Hyaluronate with 0.05% Cyclosporine in the Treatment of Dry Eye.
 JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS 33/2 :66-72,2017
 Proteomic analysis of human lacrimal and tear fluid in dry eye disease
 SCIENTIFIC REPORTS 7/ :13363-,2017
 Are Serum Vitamin D Levels Associated With Dry Eye Disease? Results From the Study Group for Environmental Eye Disease
 예방의학회지 50/6 :369-376,2017
 IOL Master 700과 500, 초음파의 안구 생체계측 및 백내장 술 후 굴절력 비교
 대한안과학회지 58/5 :523-529,2017
 Patient awareness of cataract and age-related macular degeneration among the Korean elderly: A Population-based study
 Korean Journal of Ophthalmology 31/6 :557-567,2017
 Comparison of Contact Lens Corrected Quality of Vision and Life of Keratoconus and Myopic Patients
 대한안과학회지 31/6 :489-496,2017
 Association between dry eye symptoms and suicidal ideation in a Korean adult population
 PLOS ONE 13/6 :199,131-199,145,2018
 Comparison between Wavefront-optimized and corneal Wavefront-guided Transepithelial photorefractive keratectomy in moderate to high astigmatism
 BMC OPHTHALMOLOGY 18/1 :154-,2018
 Corneal lymphangiogenesis facilitates ocular surface inflammation and cell trafficking in dry eye disease
 OCULAR SURFACE 16/3 :306-313,2018
 Comparison of Ocular Surface Mucin Expression After Topical Ophthalmic Drug Administration in Dry Eye-Induced Mouse Model
 JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS 34/9 :612-620,2018
 Downregulation of IL-7 and IL-7R reduces membrane-type matrix metalloproteinase 14 in granular corneal dystrophy type 2 keratocyte
 INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE 59/13 :5,693-5,703,2018
 Effects of Preservative-free 3% Diquafosol in Patients with Pre-existing Dry Eye Disease after Cataract Surgery: A Randomized Clinical Trial
 SCIENTIFIC REPORTS 9/1 :e12659-,2019
 A visually distinguishable light interfering bioresponsive silica nanoparticle hydrogel sensor fabricated through the molecular imprinting technique
 Journal of Materials Chemistry B 7/45 :7,067-7,248,2019 
												
					 
				 	
				
					
		
						
					저서 
					
						1. Chapter 4. Biochemistry of cornea and conjunctiva, Cornea 2nd Ed, 2007
 2. Chapter 11. RGP contact lens fitting. Clinical contact lens practice, 2nd Ed, 2007
 3. Chapter 2. Preparation of refractive surgery and patient's examination, Corneal Refractive Surgery, 1st Ed, 2006
 4. Chapter 17. Herpetic stromal disease, Atlas of cornea and external eye disease 1st Ed, 2007
 5. Chapter 8. Herpetic Keratitis, Cornea 3rd Ed, 2013,
 6. Chapter 10. Soft contact lens for astigmatic patients, Clinical contact lens practice, 3rd Ed, 2015 
												
					 
				 	
											
				
				
					
		
				
				
					타병원 동일과 LIST 
					
						
							 
							
								
								
									
									삼성서울병원 
									안성형,눈꺼풀,눈주변부종양,갑상선안증,안와 
								 
							 
							 
							
							 
							
								
								
									
									신촌세브란스 안과병원 
									노인성황반변성,당뇨망막증,망막정맥폐쇄 
								 
							 
							 
							
							 
							
							 
							
								
								
									
									서울대학교병원 
									안구건조증,각막염,백내장,각결막염,각막궤양 
								 
							 
							 
							
								
								
									
									서울아산병원 
									망막,유리체,연령관련황반변성,포도막염 
								 
							 
							 
							
							 
							
								
								
									
									건국대학교병원 
									망막,황반변성,포도막염,백내장,레이저 
								 
							 
							 
							
								
								
									
									신촌세브란스 안과병원 
									각막,백내장,수정체,굴절수술,근시교정,라식 
								 
							 
							 
							
								
								
									
									분당서울대학교병원 
									망막,포도막,황반변성,당뇨망막,망막박리 
								 
							 
							 
							
							 
							
							 
							
								
								
									
									순천향대학교 서울병원 
									황반변성,당뇨망막병증,유리체,포도막,백내장 
								 
							 
							 
							
							 
							
								
								
									
									삼성서울병원 
									당뇨망막병증,망막질환,유리체질환,황반변성 
								 
							 
							 
							
								
								
									
									서울아산병원 
									당뇨망막병증,망막유리체수술,황반변성,포도막질환 
								 
							 
							 
							
							 
							
								
								
									
									전남대학교병원 
									백내장,각막,눈물질환,눈꺼풀질환 
								 
							 
							 
							
							 
							
								
								
									
									서울아산병원 
									백내장,각막,라식,노안레이저클리닉 
								 
							 
							 
							
								
								
									
									한길안과병원 
									백내장,녹내장,각막,굴절수술,라식 
								 
							 
							 
							
							 
							
								
								
									
									서울대학교병원 
									포도막,망막,유리체질환,황반변성,황반부종 
								 
							 
							 
							
								
								
									
									부산성모안과병원 
									망막,당뇨망막병증,황반변성,포도막,유리체,백내장 
								 
							 
							 
							
							 
							
								
								
									
									신촌세브란스 안과병원 
									사시,소아안과,눈떨림,약시 
								 
							 
							 
							
							 
							
								
								
									
									신촌세브란스 안과병원 
									성형안과,눈물,의안,갑상선안병증,안검종양,혈관종 
								 
							 
							 
							
								
								
									
									가톨릭대학교 서울성모병원 
									성형안과,눈물길,눈꺼풀질환 
								 
							 
							 
							
							 
							
							 
							
							 
							
							 
							
							 
							
								
								
									
									강동경희대학교병원 
									망막유리체,황반질환,백내장,포도막염 
								 
							 
							 
							
							 
							
								
								
									
									순천향대학교 부천병원 
									망막질환,황반질환,당뇨망막병증 
								 
							 
							 
							
								
								
									
									순천향대학교 부천병원 
									특수사시,눈물샘,소아안과 
								 
							 
							 
							
													 
					 
				 	
				
		 		
        
		
	
		
				
		
                
         
        
        
        
        
        		
        
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