학력 
					연세대 의대 학사
 연세대 의대 석사
 연세대 의대 박사 
				 
			
				
				
					경력 
					1991-1993  소아내분비학  연구강사
 1993-1995  이화의대  소아과학  전임강사
 1995-1999  이화의대  소아과학  조교수
 1999-2003  미국  Oregon  Health  &  Science  University  소아과  senior  researcher
 2003-2006  연세의대  소아과학교실  부교수
 2007-현재  연세의대  소아과학교실  교수 
				 
					
				
				
					학회 
					1991-현재 대한소아과학회 회원
 1991-현재 대한내분비학회 회원
 1991-현재 대한당뇨병학회 회원
 1991-현재 대한소아내분비학회 회원
 1997-현재 미국 Endocrine Society 회원
 2001-현재 International Society for IGF Research 회원
 2004-현재 American Diabetes Association 회원
 *동아일보 선정 소아 질환분야 베스트 닥터(2000) 
				 
		
		
						
					논문 
					
						Insulin-like growth factor-binding protein 3 induces caspase-dependent apoptosis through a death receptor-mediated pathway in MCF-7 human breast cancer cells. Cancer Res 64:2229-2237, 2004
 Effect of intense exercise on inflammatory cytokines and growth mediators in adolescent boys. Pediatrics 110:681-689, 2002
 Connective tissue growth factor/IGF-binding protein-related protein-2 is a mediator in the induction of fibronectin by advanced glycosylation end-products in human dermal fibroblasts. Endocrinol 143:1260-1269, 2002.
 Effects of sodium butyrates on expression of members of the insulin-like growth factor binding protein superfamily in human mammary epithelial cells. J Endocrinol 169:97-110, 2001
 Advanced glycosylation end-products up-regulate connective tissue growth factor (IGFBP-rP2) in human fibroblast.; a potential mechanism for expansion of extracellular matrix in diabetes mellitus. Endocrinol 142:1760-1769, 2001
 Serum levels of insulin-like growth factor (IGF)-I, free IGF-I, IGF binding protein (IGFBP)-1, IGFBP-3 and insulin in obese children. J Pediatr Endocrinol Metab 12:139-144, 1999
 Identification of glycosylated 38-kDa connective tissue growth factor (IGFBP-related protein 2) and proteolytic fragments in human biological fluids, and up-regulation of IGFBP-rP2 expression by TGF in Hs 578T human breast cancer cells. J Clin Endocr Metab 83:2593-2596, 1998
 Identification of low-affinity insulin-like growth factor binding proteins (IGFBPs): Characterization of connective tissue growth factor as a member of the IGFBP superfamily. Proc Natl Acad Sci USA 94: 12981-12986, 1997
 Biological roles of insulin-like growth factor binding proteins (IGFBPs). Exp Mol Med 29:85-96, 1997
 Synthesis and characterization of insulin-like growth factor-binding protein (IGFBP)-7. J Biol Chem 271: 30322-30325, 1996
 성장호르몬 결핍증과 특발성 저신장증 환아에서 성장호르몬의 치료 효과
 KOREAN JOURNAL OF PEDIATRICS 47/3 :310-316,2004
 소아비만증에서 대사 증후군의 유병률
 KOREAN JOURNAL OF PEDIATRICS 47/11 :1149-1156,2004
 소아 제 2형 당뇨병 환아에서 Maturity Onset Diabetes of the Young(MODY) 3의 유병률에 관한 연구
 KOREAN JOURNAL OF PEDIATRICS 47/6 :641-,2004
 소아기 후천성 갑상선질환
 소아과(Korean Journal of Pediatrics) 47/9 :926-932,2004
 Insulin-LIke Growth Factor-Binding Protein 3 Induces Caspase-Dependent Apoptosis through a Death Receptor-Mediated pathway in MCF-7 Human Breast Caner Cells
 CANCER RESEARCH 64/ :2229-2237,2004
 The abnormalities of carbohydrate metabolism in Turner syndrome: Analysis of risk factors associated with impaired glucose tolerance
 EUROPEAN JOURNAL OF PEDIATRICS 164/ :442-447,2005
 소아 및 청소년 비만증에서 인슐린 저항성의 성별 차이
 대한소아내분비학회지(Journal Of Korean Society Of Pediatric Endocrinology) 10/1 :84-89,2005
 정상변이 염색체 다형현상과 동반된 저신장증
 대한소아내분비학회지(Journal Of Korean Society Of Pediatric Endocrinology) 10/1 :95-99,2005
 소아 및 청소년 비만증에서 인슐린 저항성에 미치는 요인
 소아과(Korean Journal Of Pediatrics) 48/10 :1076-1081,2005
 소아 비만증에서 비알코올성 지방간염의 유병률
 Korean Journal of Pediatrics 48/1 :13-20,2005
 한국인 선천성 부신피질과형성증의 임상적 특성
 대한소아내분비학회지(Journal Of Korean Society Of Pediatric Endocrinology) 10/2 :132-137,2005
 단순비만아에서 비만이 혈중 성장인자와 인슐린양성인자결합단백질-3의 단백분해에 미치는 영향
 대한소아내분비학회지(Journal Of Korean Society Of Pediatric Endocrinology) 10/2 :1995-203,2005
 Obesity and cardiovascular risk factors in Korean children and adolescents aged 10-18 years from the Korean National Health and Nutrition Examination Survey, 1998 and 2001
 AMERICAN JOURNAL OF EPIDEMIOLOGY 164/8 :787-793,2006
 특발성 저신장증 환자에서 성장 호르몬 투여가 당 대사에 미치는 영향
 대한소아내분비학회지(Journal Of Korean Society Of Pediatric Endocrinology) 49/6 :665-671,2006
 Association of Henoch-Scho?nlein purpura and Graves' disease [12]
 NEPHROLOGY DIALYSIS TRANSPLANTATION 21/ :2997-,2006
 조기 사춘기 여아에서 성선자극호르몬 분비호르몬 유도체가 성장과 성호르몬에 미치는 효과
 대한소아내분비학회지(Journal Of Korean Society Of Pediatric Endocrinology) 11/2 :162-169,2006
 소아에서 혈중 아연 농도가 성장에 미치는 영향
 대한소아내분비학회지(Journal Of Korean Society Of Pediatric Endocrinology) 11/2 :155-161,2006
 Prevalence of the metabolic syndrome in Korean adolescents aged 12-19 years from the Korean National Health and Nutrition Examination Survey 1998 and 2001
 DIABETES RESEARCH AND CLINICAL PRACTICE 75/ :111-114,2007
 1형 당뇨병을 가진 소아과 청소년에서 란투스 치료의 혈당 조절에 대한 효과
 소아과(Korean Journal Of Pediatrics) 50/6 :565-569,2007
 뇌종양 환아에서 성장호르몬 치료 후 뇌종양 재발증가에 관한 연구
 대한소아내분비학회지(Journal Of Korean Society Of Pediatric Endocrinology) 12/2 :99-103,2007
 성조숙증 아동의 임상 및 내분비 검사의 특징
 대한소아내분비학회지(Journal Of Korean Society Of Pediatric Endocrinology) 12/2 :119-126,2007
 성조숙증의 진단과 최신 치료 경향
 대한내분비학회지(Journal Of The Korean Society Of Endocrinology) 23/3 :165-173,2008
 당뇨병성 신증의 조기 예측 인자로서의 혈중 cystatin C 및 β2-microglobulin의 유용성
 대한소아내분비학회지(Journal Of Korean Society Of Pediatric Endocrinology) 13/2 :177-183,2008
 소아 뇌종양 수술 후 수분대사 및 전해질 장애
 Journal Of Korean Society Of Pediatric Endocrinology(대한소아내분비학회지) 14/2 :124-131,2009
 1형 당뇨병 환자에서 생리주기 이상
 Journal Of Korean Society Of Pediatric Endocrinology(대한소아내분비학회지) 14/2 :116-123,2009
 Determination of Serum Di-(2-ethylhexyl) phthalate and Bisphenol A Level in Children with Idiopathic Central Precocious Puberty
 Journal Of Korean Society Of Pediatric Endocrinology(대한소아내분비학회지) 14/2 :154-162,2009
 Clinical application of gonadotropin-releasing hormone analogs in children and adolescents
 Korean Journal of Pediatrics 53/3 :294-299,2010
 Insulin-like Growth Factor Binding Protein-3 Induces G1 Cell Cycle Arrest with Inhibition of Cyclin-dependent Kinase 2 and 4 in MCF-7 Human Breast Cancer Cells
 Hormone And Metabolic Research 42/3 :165-172,2010
 터너증후군에서 성장호르몬과 성호르몬 치료에 따른 인슐린 저항성의 변화
 Journal Of Korean Society Of Pediatric Endocrinology(대한소아내분비학회지) 15/1 :44-50,2010
 An SRY-Deleted XXY Female Resulting from a Paternally Inherited t(Y;22)
 Annals of Clinical and Laboratory Science 40/3 :295-299,2010
 Two Cases of Multiple Endocrine Neoplasia Type 2B, Early Diagnosis by Genetic Analysis and Prophylactic Total Thyroidectomy
 Journal Of Korean Society Of Pediatric Endocrinology(대한소아내분비학회지) 15/2 :138-144,2010
 소아청소년 연령에서 발생한 2형 당뇨병의 항췌도 자가항체 유무에 따른 임상적 특성
 Journal Of Korean Society Of Pediatric Endocrinology(대한소아내분비학회지) 15/2 :93-99,2010
 Identification of a Novel Cell Death Receptor Mediating IGFBP-3-induced Anti-tumor Effects in Breast and Prostate Cancer
 The Journal of biological chemistry 285/39 :30233-30246,2010
 Effects of a Structured Exercise Program on Insulin Resistance, Inflammatory Markers and Physical Fitness in Obese Korean Children
 Journal of Pediatric Endocrinology & Metabolism 23/10 :1065-1072,2010
 부갑상샘저하증과 거짓 부갑상샘저하증의 임상적 특성
 Journal Of Korean Society Of Pediatric Endocrinology(대한소아내분비학회지) 15/3 :181-186,2010
 1형 당뇨병 소아환자에서 발생한 원발성 국소분절사구체경화증 1례
 Journal Of Korean Society Of Pediatric Endocrinology(대한소아내분비학회지) 15/3 :203-206,2010
 Effects of Body Composition, Leptin, and Adiponectin on Bone Mineral Density in Prepubertal Girls
 JOURNAL OF KOREAN MEDICAL SCIENCE 25/8 :1187-1190,2010
 Noonan 증후군과 성장호르몬결핍증 환아에서 성장호르몬 치료 효과
 대한소아내분비학회지 16/2 :100-105,2011
 Serum Kisspeptin Levels in Korean Girls with Central Precocious Puberty
 JOURNAL OF KOREAN MEDICAL SCIENCE 26/7 :927-931,2011
 Insulin-Like Growth Factor-Binding Protein-3 Mediates High Glucose-Induced Apoptosis by Increasing Oxidative Stress in Proximal Tubular Epithelial Cells
 ENDOCRINOLOGY 152/8 :3135-3142,2011
 Frequencies and Related Factors for Microvascular Complications in Patients with Type 1 Diabetes
 Annals of Pediatric Endocrinology & Metabolism 17/1 :16-26,2012
 Reference values for serum levels of insulin-like growth factor-I and insulin-like growth factor binding protein-3 in Korean children and adolescents
 CLINICAL BIOCHEMISTRY 45/1-2 :16-21,2012
 Spot urine albumin to creatinine ratio and serum cystatin C are effective for detection of diabetic nephropathy in childhood diabetic patients
 JOURNAL OF KOREAN MEDICAL SCIENCE 27/7 :784-787,2012
 Hypodipsic hypernatremia leading to reversible renal failure following surgery for craniopharyngioma
 JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM 25/9-10 :1027-1030,2012
 Proton-Pump Inhibitor-Induced Hypocalcemia and Hypomagnesemia
 대한소아내분비학회지 17/4 :249-252,2012
 IGFBP-3 Inhibits Cytokine-Induced Insulin Resistance and Early Manifestations of Atherosclerosis
 PLOS ONE 8/1 :e55084-e55084,2013
 Longitudinal Standards for Height and Height Velocity in Korean Children and Adolescents: the Kangwha Cohort Study
 JOURNAL OF KOREAN MEDICAL SCIENCE 28/10 :1512-1517,2013
 The Clinical Measures Associated with C-peptide Decline in Patients with Type 1 Diabetes over 15 Years
 JOURNAL OF KOREAN MEDICAL SCIENCE 28/9 :1340-1344,2013
 Final height and insulin-like growth factor-1 in children with medulloblastoma treated with growth hormone
 CHILDS NERVOUS SYSTEM 29/10 :1859-1863,2013
 Efficacy and safety of LB03002, a once-weekly sustained-release human GH for 12-month treatment in Korean children with GH deficiency
 EUROPEAN JOURNAL OF ENDOCRINOLOGY 169/2 :179-185,2013
 Sex hormone binding globulin, free estradiol index, and lipid profiles in girls with precocious puberty
 Annals of Pediatric Endocrinology & Metabolism 18/2 :81-84,2013
 Factors that predict a positive response on gonadotropin-releasing hormone stimulation test for diagnosing central precocious puberty in girls
 Annals of Pediatric Endocrinology & Metabolism 18/4 :202-207,2013
 Role of insulin-like growth factor binding protein-3 in glucose and lipid metabolism
 Annals of Pediatric Endocrinology & Metabolism 18/1 :9-12,2013
 Efficacy of Short-Term Growth Hormone Treatment in Prepubertal Children with Idiopathic Short Stature
 YONSEI MEDICAL JOURNAL 55/1 :53-60,2014
 Establishing pediatric reference intervals for 13 biochemical analytes derived from normal subjects in a pediatric endocrinology clinic in Korea
 CLINICAL BIOCHEMISTRY 47/18 :268-271,2014
 KISS1 Gene Polymorphisms in Korean Girls with Central Precocious Puberty
 JOURNAL OF KOREAN MEDICAL SCIENCE 29/8 :1120-1125,2014
 A case of thyrotoxic periodic paralysis as initial manifestation of Graves' disease in a 16-year-old Korean adolescent
 Annals of Pediatric Endocrinology & Metabolism 19/3 :169-173,2014
 Adult height in girls with central precocious puberty treated with gonadotropin-releasing hormone agonist with or without growth hormone
 Annals of Pediatric Endocrinology & Metabolism 19/4 :214-219,2014
 Growth hormone treatment and risk of malignancy
 Korean Journal of Pediatrics 58/2 :41-46,2015
 Regression and progression of microalbuminuria in adolescents with childhood onset diabetes mellitus
 Annals of Pediatric Endocrinology & Metabolism 20/1 :13-20,2015
 Etiologies and characteristics of children with chief complaint of short stature
 Annals of Pediatric Endocrinology & Metabolism 20/1 :34-39,2015
 Relationship between serum 25-hydroxyvitamin D concentration and risks of metabolic syndrome in children and adolescents from Korean National Health and Nutrition Examination survey 2008?2010
 Annals of Pediatric Endocrinology & Metabolism 20/1 :46-52,2015
 Clinical manifestations of testicular adrenal rest tumor in males with congenital adrenal hyperplasia
 Annals of Pediatric Endocrinology & Metabolism 20/3 :155-161,2015
 Hypotonic hyponatremia by primary polydipsia caused brain death in a 10-year-old boy
 Annals of Pediatric Endocrinology & Metabolism 20/3 :166-169,2015
 XYY syndrome: a 13-year-old boy with tall stature
 Annals of Pediatric Endocrinology & Metabolism 20/3 :170-173,2015
 Turner syndrome with spinal hemorrhage due to vascular malformation
 Annals of Pediatirc Endocrinology & Metabolism 20/4 :235-237,2015
 Burkholderia Sepsis in Children as a Hospital-Acquired Infection
 YONSEI MEDICAL JOURNAL 57/1 :97-102,2016
 Ultrasound measurement of pediatric visceral fat thickness: correlations with metabolic and liver profiles
 Annals of Pediatirc Endocrinology & Metabolism 21/2 :75-80,2016
 Male patients presenting with rapidly progressive puberty associated with malignant tumors.
 Annals of Pediatric Endocrinology & Metabolism 21/1 :51-55,2016
 A patient with Cushing disease lateralizing a pituitary adenoma by inferior petrosal sinus sampling using desmopressin
 Annals of Pediatric Endocrinology & Metabolism 21/1 :43-46,2016
 Human Coronavirus in the 2014 Winter Season as a Cause of Lower Respiratory Tract Infection
 YONSEI MEDICAL JOURNAL 58/1 :174-179,2017
 Elevated serum YKL-40 levels in patients with Kawasaki disease
 BIOMARKERS 22/3-4 :326-330,2017
 Diabetes mellitus due to agenesis of the dorsal pancreas in a patient with heterotaxy syndrome
 Annals of Pediatirc Endocrinology & Metabolism 22/2 :125-128,2017
 Risk of Gonadoblastoma Development in Patients with Turner Syndrome with Cryptic Y Chromosome Material
 HORMONES & CANCER 8/3 :166-173,2017
 Clinical manifestations of Rathke’s cleft cysts and their natural progression during 2 years in children and adolescents
 Annals of Pediatirc Endocrinology & Metabolism 22/3 :164-169,2017
 A 1-month-old infant with chylomicronemia due to GPIHBP1 gene mutation treated by plasmapheresis
 Annals of Pediatirc Endocrinology & Metabolism 22/1 :68-71,2017
 Insulin resistance and bone age advancement in girls with central precocious puberty
 Annals of Pediatirc Endocrinology & Metabolism 22/3 :176-182,2017
 A boy with 46,X,+mar presenting gynecomastia and short stature
 Annals of Pediatirc Endocrinology & Metabolism 22/4 :266-271,2017
 Once-Weekly Administration of Sustained-Release Growth Hormone in Korean Prepubertal Children with Idiopathic Short Stature: A Randomized, Controlled Phase II Study
 HORMONE RESEARCH IN PAEDIATRICS 90/1 :54-63,2018
 Visceral fat thickness and its associations with pubertal and metabolic parameters among girls with precocious puberty
 Annals of Pediatirc Endocrinology & Metabolism 23/2 :81-87,2018
 Respiratory failure in a diabetic ketoacidosis patient with severe hypophosphatemia
 Annals of Pediatirc Endocrinology & Metabolism 23/2 :103-106,2018
 Effect of Growth Hormone Therapy on Height Velocity in Korean Children with Idiopathic Short Stature: A Phase III Randomised Controlled Trial
 HORMONE RESEARCH IN PAEDIATRICS 90/1 :44-53,2018
 Recombinant growth hormone therapy for prepubertal children with idiopathic short stature in Korea: a phase III randomized trial
 JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION 41/4 :475-483,2018
 Effect of the Orally Active Growth Hormone Secretagogue MK-677 on Somatic Growth in Rats
 YONSEI MEDICAL JOURNAL 59/10 :1,174-1,180,2018
 Incidence and Prevalence of Central Precocious Puberty in Korea: An Epidemiologic Study Based on a National Database
 JOURNAL OF PEDIATRICS 208/18 :221-228,2019
 Long-term safety and effectiveness of growth hormone therapy in Korean children with growth disorders: 5-year results of LG Growth Study
 PLOS ONE 14/5 :e0216927-,2019
 제1형 당뇨병 청소년의 자기관리 영향요인: 정보-동기-행동기술 모델을 기반으로
 Child Health Nursing Research 25/2 :234-243,2019
 Fructose-1,6-bisphosphatase deficiency presented with complex febrile convulsion
 NEUROENDOCRINOLOGY LETTERS 39/8 :533-536,2019
 The analysis of endocrine disruptors in patients with central precocious puberty
 BMC PEDIATRICS 19/1 :e323-,2019
 Final Adult Height after Growth Hormone Treatment in Patients with Turner Syndrome
 HORMONE RESEARCH IN PAEDIATRICS 91/6 :373-379,2019
 Healthcare transition readiness, family support, and self-management competency in Korean emerging adults with Type 1 diabetes mellitus
 JOURNAL OF PEDIATRIC NURSING-NURSING CARE OF CHILDREN & FAMILIES 48/ :e1-e7,2019 
												
					 
				 	
				
					
		
				
				
				
					동병원 동일과 LIST 
					
						
							 
							
								
								
									
									천성기형,희귀질환,대사질환,유전자검사,성장장애 
									
																				월요일오후 	
										화요일오전 		
										화요일오후 	
												
										수요일오후 		
										목요일오전 		
										목요일오후 		
												
												
												
																						
									 
								 
							 
							 
							
													 
					 
				 	
		
				
				
					타병원 동일과 LIST 
					
						
							 
							
								
								
									
									화순전남대학교병원 
									소아혈액종양학,조혈모세포이식,면역결핍질환 
								 
							 
							 
							
								
								
									
									신촌세브란스 연세암병원 
									소아청소년암,백혈병,육종,혈우병 
								 
							 
							 
							
								
								
									
									부산대학교 어린이병원 
									선천성심장병,중재적심도자술,태아심장 
								 
							 
							 
							
								
								
									
									삼성서울병원 
									자궁내발육지연,미숙아,고위험신생아,신생아질환 
								 
							 
							 
							
							 
							
								
								
									
									소화병원 
									알레르기,호흡기,아토피,두드러기,만성비염 
								 
							 
							 
							
								
								
									
									한양대학교 구리병원 
									알라르기비염,아토피피부염,면역질환,천식 
								 
							 
							 
							
							 
							
								
								
									
									한양대학교병원 
									소아혈액종양,조혈모세포이식,제대혈이식,세포치료 
								 
							 
							 
							
								
								
									
									이대목동병원 
									소아청소년감염,예방접종,불명열,결핵,발진질환 
								 
							 
							 
							
								
								
									
									인제대학교 상계백병원 
									성장장애,당뇨병,소아청소년비만 
								 
							 
							 
							
								
								
									
									서울아산병원 
									소아뇌종양,두개안면기형,모야모야병,수두증 
								 
							 
							 
							
								
								
									
									강동경희대학교병원 
									성장,발달클리닉,발달지연,소아신경질환 
								 
							 
							 
							
							 
							
								
								
									
									순천향대학교 서울병원 
									소아알레르기,천식,아토피피부염 
								 
							 
							 
							
								
								
									
									서울아산병원 
									선천성심장병,비수술적중재시술,소아심장이식 
								 
							 
							 
							
								
								
									
									삼성서울병원 
									혈모세포이식,소아암,백혈병,빈혈,혈소판감소증 
								 
							 
							 
							
								
								
									
									삼성서울병원 
									신경모세포종,뇌종양,소아암,조혈모세포이식 
								 
							 
							 
							
								
								
									
									가톨릭대학교 서울성모병원 
									소아뇌전증,경련성 질환,두통,뇌성마비,근육질환 
								 
							 
							 
							
								
								
									
									가톨릭대학교 서울성모병원 
									성조숙증,갑상선,당뇨 
								 
							 
							 
							
								
								
									
									가톨릭대학교 서울성모병원 
									백혈병,림프종,재생불량빈혈,소아청소년암 
								 
							 
							 
							
								
								
									
									고려대학교 구로병원 
									신장요로질환,요로감염,고혈압 
								 
							 
							 
							
								
								
									
									고려대학교 구로병원 
									소아신경질환,뇌전증,뇌성마비,두통,발달지연 
								 
							 
							 
							
							 
							
								
								
									
									고려대학교 안암병원 
									소아혈액종양,백혈병,빈혈,혈액질환 
								 
							 
							 
							
								
								
									
									중앙대학교병원 
									소아신장,소아내분비,소아비만,야뇨증,성장 
								 
							 
							 
							
								
								
									
									중앙대학교병원 
									소아신경질환,소아경련성질환,실신 
								 
							 
							 
							
							 
							
							 
							
								
								
									
									강남세브란스병원 
									저신장,성조숙증,소아비만,소아당뇨,내분비질환 
								 
							 
							 
							
							 
							
								
								
									
									순천향대학교 부천병원 
									소아혈액종양학,소아신장학 
								 
							 
							 
							
							 
							
								
								
									
									순천향대학교 부천병원 
									소아내분비질환,유전질환,대사질환 
								 
							 
							 
							
								
								
									
									동국대학교 일산병원 
									아신경,뇌전증,간질,두통,어지럼증,실신,발달지연 
								 
							 
							 
							
								
								
									
									동국대학교 일산병원 
									신생아,미숙아,감염질환,호흡기질환 
								 
							 
													 
					 
				 	
				
		 		
        
		
	
		
				
		
                
         
        
        
        
        
        		
        
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