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교수찾아삼만리

이홍규

이홍규 교수

Dr. Lee Hong Gyu
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내분비내과
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1899-0001
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학력

서울대학교 의과대학 졸업
서울대학교 대학원 의학과 졸업- 의학박사

경력

서울대학교 의과대학 내분비대 내과 분과장 (2009년 정년) 현 명예교수
국립보건원 생명의학부 부장 역임

학회

대한 당뇨병학회, 대한 내분비학회 회장 역임
아시아당뇨병학회 부이사장
한국 소아당뇨병협회 명예 이사장

논문

1. IS Song, J Han, HK Lee. Metformin as an anticancer drug; A Commentary on the “Metabolic determinants of cancer cell sensitivity to glucose limitation and biguanides”. Journal of Diabetes Investigation, 6(5):516-8, 2015

2. JT Kim, HK Lee. Metabolic syndrome and the environmental pollutants from mitochondrial perspectives. Reviews Endocrine Metabolic Disorders 15 (4), 253-262, 2014

3. E Roh, SH Kwak, HS Jung, YM Cho, YK Pak, KS Park, SY Kim, HK Lee. Serum aryl 3hydrocarbon receptor ligand activity is associated with insulin resistance and resulting type 2 diabetes. Acta Diabetologica, 1-7, 2014

4. HK Lee. Success of 2013–2020 World Health Organization action plan to control non‐communicable diseases would require pollutants control. Journal Diabetes Investigation, 5 (6), 621-622, 2014

5. HK Lee. Advances around technologies investigating mitochondrial function and insights gained by their applications. Journal Diabetes Investigation 5 (2), 144-146, 2014

6. JT Kim, SS Kim, DW Jun, YH Hwang, WH Park, YK Pak, HK Lee. Serum arylhydrocarbon receptor transactivating activity is elevated in type 2 diabetic patients with diabetic nephropathy. Journal Diabetes Investigation 4 (5), 483-491, 2013

7. WH Park, DW Jun, JT Kim, JH Jeong, H Park, YS Chang, KS Park, HK Lee,. Novel cell‐based assay reveals associations of circulating serum AhR‐ligands with metabolic syndrome and mitochondrial dysfunction. BioFactors 39 (4), 494-504, 2013

8. MH Park, SH Kwak, KJ Kim, MJ Go, HJ Lee, KS Kim, JY Hwang, K Kimm, YM Cho, HK Lee, KS Park, JY Lee. Identification of a genetic locus on chromosome 4q34-35 for type 2 diabetes with overweight. Experimental Molecular Medicine 45 (2), e7, 2013

9. HK Lee, EB Shim. Extension of the mitochondria dysfunction hypothesis of metabolic syndrome to atherosclerosis with emphasis on the endocrine‐disrupting chemicals and biophysical laws. Journal of Diabetes Investigation 4 (1), 19-33, 2013

10. Y Hwangbo, JT Kim, EK Kim, AR Khang, TJ Oh, HC Jang, KS Park, SY Kim, HK Lee, YM Cho. Prevalence and clinical characteristics of recently diagnosed type 2 diabetes patients with positive anti-glutamic acid decarboxylase antibody. Diabetes Metabolism Journal 36 (2), 136-143, 2012

11. JK Jung, HJ Kim, HK Lee, SS Kim, CS Shin, JT Kim. Fracture incidence and risk of osteoporosis in female type 2 diabetic patients in Korea. Diabetes Metabolism Journal 36 (2), 144-150, 2012

12. J Jin, YH Ku, Y Kim, Y Kim, K Kim, JY Lee, YM Cho, HK Lee, KS Park, Y Kim. Differential proteome profiling using iTRAQ in microalbuminuric and normoalbuminuric type 2 diabetic patients. Experimental Diabetes Research 2012:168602. doi: 10.1155/2012/168602

13. YM Cho, JH Kim, M Kim, SJ Park, SH Koh, HS Ahn, GH Kang, JB Lee, KS Park, HK Lee. .Mesenchymal stem cells transfer mitochondria to the cells with virtually no mitochondrial function but not with pathogenic mtDNA mutations. PloS one 7 (3), e32778, 2012

14. YY Lee, HJ Lee, SS Lee, JS Koh, CJ Jin, SH Park, KH Yi, KS Park, HK Lee. Taurine supplementation restored the changes in pancreatic islet mitochondria in the fetal protein-malnourished rat. British Journal of Nutrition 106 (08), 1198-1206, 2011

15. S Lim, SH Choi, BK Koo, SM Kang, JW Yoon, HC Jang, SM Choi, MG Lee, W Lee, H Shin, YB Kim, HK Lee, KS Park KS. Effects of aerobic exercise training on C1q tumor necrosis factor α-related protein isoform 5 (myonectin): association with insulin resistance and mitochondrial DNA density in women. Journal of Clinical Endocrinology Metabolism 97 (1), E88-E93, 2011

16. S Hwang, SH Kwak, J Bhak, HS Kang, YR Lee, BK Koo, KS Park, HK Lee. Gene expression pattern in transmitochondrial cytoplasmic hybrid cells harboring type 2 diabetes-associated mitochondrial DNA haplogroups. PloS one 6 (7), e22116, 2011

17. HI Kim, JT Kim, SH Yu, SH Kwak, HC Jang, KS Park, SY Kim, HK Lee. Gender differences in diagnostic values of visceral fat area and waist circumference for predicting metabolic syndrome in Koreans. Journal of Korean medical science 26 (7), 906-913 7, 2011

18. HK Lee. Mitochondrial dysfunction and insulin resistance: the contribution of dioxin-like substances. Diabetes Metabolism Journal 35 (3), 207-215, 2011

19. S Lim, H Shin, JH Song, SH Kwak, SM Kang, JW Yoon, SH Choi, SI Cho, KS Park, HK Lee, HC Jang, KK Koh. Increasing Prevalence of Metabolic Syndrome in Korea The Korean National Health and Nutrition Examination Survey for 1998–2007. Diabetes Care 34 (6), 1323-1328, 2011

20. TH Kim, SH Yu, SH Choi, JW Yoon, SM Kang, EJ Chun, SI Choi, H Shin, HK Lee, KS Park, HC Jang, S Lim. Pericardial Fat Amount Is an Independent Risk Factor of Coronary Artery Stenosis Assessed by Multidetector‐Row Computed Tomography: The Korean Atherosclerosis Study. Obesity 19 (5), 1028-1034, 2011

21. JT Kim, TJ Oh, YA Lee, JH Bae, HJ Kim, HS Jung, YM Cho, KS Park, S Lim, HC Jang, HKLee. Increasing trend in the number of severe hypoglycemia patients in Korea. Diabetes Metabolism Journal 35 (2), 166-172, 2011

22. CH Youn, EB Shim, S Lim, YM Cho, HK Hong, YS Choi, HD Park, HK Lee. A cooperative metabolic syndrome estimation with high precision sensing unit. Biomedical Engineering, IEEE Transactions on 58 (3), 809-813, 2011

23. S Lira, H Shin, JH Song, HK Lee. Increasing prevalence of metabolic syndrome in Korea: the Korea National Health and Nutrition Exam-ination Survey for 1998-2007. Diabetes Care 34 (6), 1323-8, 2011

24. IK Jeong, SW Cho, SW Kim, HJ Choi, KS Park, SY Kim, HK Lee, SH Cho, BH Oh, CS Shin. Lipid profiles and bone mineral density in pre-and postmenopausal women in Korea. Calcified Tissue International, 87 (6), 507-512, 2010

25. SH Han, SH Choi, BJ Cho, Y Lee, S Lim, YJ Park, MK Moon, HK Lee, ...Serum fibroblast growth factor–21 concentration is associated with residual renal function and insulin resistance in end-stage renal disease patients receiving long-term peritoneal dialysis. Metabolism 59 (11), 1656-1662, 2010

26. CH Youn, DH Kim, EB Shim, YS Choi, JS Park, S Lim, HC Jang, HK Lee. Kepler-based collaborative workflow system for metabolic syndrome estimation. TENCON 2010-2010 IEEE Region 10 Conference, 1481-1485, 2010

27. JS Yang, JT Kim, J Jeon, HS Park, GH Kang, KS Park, HK Lee, S Kim, ...Changes in hepatic gene expression upon oral administration of taurine-conjugated ursodeoxycholic acid in ob/ob mice. PloS One 5 (11), e13858, 2010

28. SH Kwak, KS Park, KU Lee, HK Lee. Mitochondrial metabolism and diabetes. Journal of Diabetes Investigation, 1 (5), 161-169, 2010

29. BK Koo, YM Cho, K Kimm, JY Lee, B Oh, BL Park, HS Cheong, HD Shin, ...Polymorphisms of the Reg1α Gene and Early Onset Type 2 Diabetes in the Korean Population. Korean Diabetes Journal 34 (4), 229-236, 2010

30. HK Lee. Persistent organic pollutants and epidemic of diabetes and metabolic syndrome. Journal of diabetes investigation, 1 (4), 121-122, 2010

31. YM Cho, BK Koo, HY Son, KW Lee, HS Son, DS Choi, BW Kim, YK Kim, ...Effect of the combination of mitiglinide and metformin on glycemic control in patients with type 2 diabetes mellitus. Journal Diabetes Investigation, 1 (4), 143-148, 2010

32. JH An, JY Yang, BY Ahn, SW Cho, JY Jung, HY Cho, YM Cho, SW Kim, ...Enhanced mitochondrial biogenesis contributes to Wnt induced osteoblastic differentiation of C3H10T1/2 cells. Bone 47 (1), 140-150, 2010

33. S Lim, YM Cho, KS Park, HK Lee. Persistent organic pollutants, mitochondrial dysfunction, and metabolic syndrome. Annals New York Academy Sciences, 1201 (1), 166-176, 2010

34. SS Chung, BY Ahn, M Kim, HH Choi, HS Park, S Kang, SG Park, YB Kim, ... Control of adipogenesis by the SUMO-specific protease SENP2. Molecular Cellular Biology 30 (9), 2135-2146, 2010

35. S Lim, JW Yoon, SH Choi, YJ Park, JJ Lee, JH Park, SB Lee, KW Kim, ... Combined Impact of Adiponectin and Retinol‐binding Protein 4 on Metabolic Syndrome in Elderly People: The Korean Longitudinal Study on Health and Aging. Obesity 18 (4), 826-832, 2010

36. HK Lee, YM Cho, SH Kwak, S Lim, KS Park, EB Shim. Mitochondrial dysfunction and metabolic syndrome—looking for environmental factors. Biochimica Biophysica Acta -General Subjects, 1800 (3), 282-289, 2010

37. MK Moon, M Kim, SS Chung, HJ Lee, SH Koh, P Svovoda, MH Jung, ... S-Adenosyl-L-methionine ameliorates TNFα-induced insulin resistance in 3T3-L1 adipocytes. Experimental Molecular Medicine, 42 (5), 345-352, 2010

38. JE Shim, HY Paik, CS Shin, KS Park, HK Lee. Vitamin C nutriture in newly diagnosed diabetes. Journal Nutritional Science Vitaminology, 56 (4), 217-221, 2010

저서

- 당뇨인의 건강수첩 1984. 일조각 (역편)
- 딜레마게임 1990. 고려의학 (편역)
- Diabetes in Western Pacific Region 1993. 고려의학 (공편)
- 내분비의학 1994. 의학출판사 (공편)
- 의사들의 생각 1994. 고려의학 (번역)
- 내과학 총론 1999. 고려의학 (공저)
- 생명의 에너지 (가이 브라운 저). 2002. 한의학 (공역)
- 내과학 2005 최신지견. 고려의학 (공저)
- 당뇨병학. 제3판. 대한당뇨병학회. (공저)
- Mitochondria in Health and Disease. Dekker, USA, 2005. (공저)
- Mitochondrial Pathogenesis- From Genes and Apoptosis to Aging and Disease.
Annals of New York Academy of Sciences vol 1011. 2005 (편저).
- 바이칼에서 찾는 우리민족의 기원. 정신세계원. 2005. (편저)
- 일본인의 조상, 한국인의 조상. 시노다 겐이치 (저), 박명미 (번역), 보고사, 2008 (감수 및 서문)
- 한국인의 기원, 한국역사재단. 2010 (저서)
- 몸이 젊어지는 기술. 청림라이프, 2100 (오타 시게오 전, 김영설, 이홍규 공역)
- 당뇨, 기적의 밥상. 싸이프레스 2014. (장학철, 조영연 공저)

참고

1999. 서울시 의사회 유한의학상
2005. 대한내분비학회 남곡학술상
2008. 서울대학교 30년 근속표창
2009. 녹조근정훈장
2010. 대한당뇨병학회 설원학술상
2015. 교육부총리 표창 - 소아당뇨협회의 발전에 기여한 공로

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