I got Thermage 600 shots + Rejuran 2cc once and then Rejuran 2cc once more separately. I thought Thermage wouldn't hurt, but it was actually painful and Rejuran really hurt, but it was bearable because it finished quickly. I did n't time it, but it felt like Thermage took about 15 minutes and Rejuran took about 1 minute? I'm not sure if there's a difference since I didn't attach a separate photo review. I plan to get both consistently for long-term management, but I don't think there's anything that's really noticeable.